| Background: | The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The function of this mitochondrial protein is unknown. |
| UniProt Protein Function: | ABCB10: May mediate critical mitochondrial transport functions related to heme biosynthesis. Belongs to the ABC transporter superfamily. ABCB family. Mitochondrial peptide exporter (TC 3.A.1.212) subfamily. |
| UniProt Protein Details: | Protein type:Transporter; Membrane protein, multi-pass; Mitochondrial; Membrane protein, integral; Hydrolase; Transporter, ABC family Chromosomal Location of Human Ortholog: 1q42.13 Molecular Function:ATPase activity, coupled to transmembrane movement of substances Biological Process: transmembrane transport |
| NCBI Summary: | The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The function of this mitochondrial protein is unknown. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q9NRK6 |
| NCBI GenInfo Identifier: | 171184400 |
| NCBI Gene ID: | 23456 |
| NCBI Accession: | NP_036221.2 |
| UniProt Secondary Accession: | Q9NRK6,Q13040, Q6P1Q8, Q9H3V0, |
| UniProt Related Accession: | Q9NRK6 |
| Molecular Weight: | 79,148 Da |
| NCBI Full Name: | ATP-binding cassette sub-family B member 10, mitochondrial |
| NCBI Synonym Full Names: | ATP binding cassette subfamily B member 10 |
| NCBI Official Symbol: | ABCB10 |
| NCBI Official Synonym Symbols: | M-ABC2; MTABC2; EST20237 |
| NCBI Protein Information: | ATP-binding cassette sub-family B member 10, mitochondrial |
| UniProt Protein Name: | ATP-binding cassette sub-family B member 10, mitochondrial |
| UniProt Synonym Protein Names: | ATP-binding cassette transporter 10; ABC transporter 10 protein; Mitochondrial ATP-binding cassette 2; M-ABC2 |
| Protein Family: | ABC transporter B family |
| UniProt Gene Name: | ABCB10 |
| UniProt Entry Name: | ABCBA_HUMAN |
