Anti-A4GNT Antibody (CAB12366)
- SKU:
- CAB12366
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Signal Transduction
Frequently bought together:
Description
| Antibody Name: | Anti-A4GNT Antibody |
| Antibody SKU: | CAB12366 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-340 of human A4GNT (NP_057245.1). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human |
| Positive Samples: | SGC-7901, 293T, LO2 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-340 of human A4GNT (NP_057245.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MRKE LQLS LSVT LLLV CGFL YQFT LKSS CLFC LPSF KSHQ GLEA LLSH RRGI VFLE TSER MEPP HLVS CSVE SAAK IYPE WPVV FFMK GLTD STPM PSNS TYPA FSFL SAID NVFL FPLD MKRL LEDT PLFS WYNQ INAS AERN WLHI SSDA SRLA IIWK YGGI YMDT DVIS IRPI PEEN FLAA QASR YSSN GIFG FLPH HPFL WECM ENFV EHYN SAIW GNQG PELM TRML RVWC KLED FQEV SDLR CLNI SFLH PQRF YPIS YREW RRYY EVWD TEPS FNVS YALH LWNH MNQE GRAV IRGS NTLV ENLY RKHC PRTY RDLI KGPE GSVT GELG PGNK |
| Gene ID: | 51146 |
| Uniprot: | Q9UNA3 |
| Cellular Location: | Golgi apparatus membrane, Single-pass type II membrane protein |
| Calculated MW: | 39kDa |
| Observed MW: | 37kDa |
| Synonyms: | A4GNT, alpha4GnT, alpha-1 |
| Background: | This gene encodes a protein from the glycosyltransferase 32 family. The enzyme catalyzes the transfer of N-acetylglucosamine (GlcNAc) to core 2 branched O-glycans. It forms a unique glycan, GlcNAcalpha1-->4Galbeta-->R and is largely associated with the Golgi apparatus membrane. |
| UniProt Protein Function: | A4GNT: Necessary for the synthesis of type III mucin. Catalyzes the transfer of N-acetylglucosamine (GlcNAc) to core 2 branched O- glycans. Belongs to the glycosyltransferase 32 family. |
| UniProt Protein Details: | Protein type:EC 2.4.1.-; Membrane protein, integral; Transferase Chromosomal Location of Human Ortholog: 3q22.3 Cellular Component: Golgi membrane; membrane Molecular Function:acetylglucosaminyltransferase activity Biological Process: carbohydrate metabolic process; glycoprotein biosynthetic process; O-glycan processing; protein amino acid O-linked glycosylation |
| NCBI Summary: | This gene encodes a protein from the glycosyltransferase 32 family. The enzyme catalyzes the transfer of N-acetylglucosamine (GlcNAc) to core 2 branched O-glycans. It forms a unique glycan, GlcNAcalpha1-->4Galbeta-->R and is largely associated with the Golgi apparatus membrane. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q9UNA3 |
| NCBI GenInfo Identifier: | 25452797 |
| NCBI Gene ID: | 51146 |
| NCBI Accession: | Q9UNA3.1 |
| UniProt Secondary Accession: | Q9UNA3,Q0VDK1, Q0VDK2, |
| UniProt Related Accession: | Q9UNA3 |
| Molecular Weight: | 39kDa |
| NCBI Full Name: | Alpha-1,4-N-acetylglucosaminyltransferase |
| NCBI Synonym Full Names: | alpha-1,4-N-acetylglucosaminyltransferase |
| NCBI Official Symbol: | A4GNT |
| NCBI Official Synonym Symbols: | alpha4GnT |
| NCBI Protein Information: | alpha-1,4-N-acetylglucosaminyltransferase |
| UniProt Protein Name: | Alpha-1,4-N-acetylglucosaminyltransferase |
| Protein Family: | Alpha-1,4-N-acetylglucosaminyltransferase |
| UniProt Gene Name: | A4GNT |
 | Western blot analysis of extracts of various cell lines, using A4GNT antibody (CAB12366) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s. |
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