Anti-A4GALT Antibody (CAB8817)
- SKU:
- CAB8817
- Product type:
- Antibody
- Application:
- WB
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Metabolism
Frequently bought together:
Description
| Antibody Name: | Anti-A4GALT Antibody |
| Antibody SKU: | CAB8817 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 244-353 of human A4GALT (NP_059132.1). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | 293T, LO2, A375, HeLa, Mouse kidney, Mouse brain, Rat kidney |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 244-353 of human A4GALT (NP_059132.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | WIWG HQGP QLLT RVFK KWCS IRSL AESR ACRG VTTL PPEA FYPI PWQD WKKY FEDI NPEE LPRL LSAT YAVH VWNK KSQG TRFE ATSR ALLA QLHA RYCP TTHE AMKM YL |
| Gene ID: | 53947 |
| Uniprot: | Q9NPC4 |
| Cellular Location: | Golgi apparatus membrane, Single-pass type II membrane protein |
| Calculated MW: | 40kDa |
| Observed MW: | 45kDa |
| Synonyms: | A4GALT, A14GALT, A4GALT1, Gb3S, P(k), P1, P1PK, PK |
| Background: | The protein encoded by this gene catalyzes the transfer of galactose to lactosylceramide to form globotriaosylceramide, which has been identified as the P(k) antigen of the P blood group system. This protein, a type II membrane protein found in the Golgi, is also required for the synthesis of the bacterial verotoxins receptor. Alternatively spliced transcript variants have been found for this gene. |
| UniProt Protein Function: | ACTA2: Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. Polymerization of globular actin (G-actin) leads to a structural filament (F-actin) in the form of a two-stranded helix. Each actin can bind to 4 others. Up-regulated in response to enterovirus 71 (EV71) infection. Belongs to the actin family. |
| UniProt Protein Details: | Protein type:Contractile; Motility/polarity/chemotaxis; Cytoskeletal Chromosomal Location of Human Ortholog: 10q23.3 Cellular Component: extracellular space; smooth muscle contractile fiber; protein complex; cytoplasm; cytosol; actin cytoskeleton Molecular Function:protein kinase binding; ATP binding Biological Process: muscle contraction; regulation of blood pressure; response to virus; vascular smooth muscle contraction Disease: Moyamoya Disease 5; Multisystemic Smooth Muscle Dysfunction Syndrome; Aortic Aneurysm, Familial Thoracic 6 |
| NCBI Summary: | The protein encoded by this gene catalyzes the transfer of galactose to lactosylceramide to form globotriaosylceramide, which has been identified as the P(k) antigen of the P blood group system. This protein, a type II membrane protein found in the Golgi, is also required for the synthesis of the bacterial verotoxins receptor. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Dec 2015] |
| UniProt Code: | Q9NPC4 |
| NCBI GenInfo Identifier: | 8392830 |
| NCBI Gene ID: | 53947 |
| NCBI Accession: | NP_059132 |
| UniProt Related Accession: | Q9NPC4 |
| Molecular Weight: | 40kDa |
| NCBI Full Name: | lactosylceramide 4-alpha-galactosyltransferase |
| NCBI Synonym Full Names: | alpha 1,4-galactosyltransferase (P blood group) |
| NCBI Official Symbol: | A4GALT |
| NCBI Official Synonym Symbols: | P1; PK; Gb3S; P(k); P1PK; A14GALT; A4GALT1 |
| NCBI Protein Information: | lactosylceramide 4-alpha-galactosyltransferase |
| UniProt Protein Name: | Actin, aortic smooth muscle |
| UniProt Synonym Protein Names: | Alpha-actin-2; Cell growth-inhibiting gene 46 protein |
| Protein Family: | Actin |
| UniProt Gene Name: | ACTA2 |
| UniProt Entry Name: | ACTA_HUMAN |
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