GenieFluor 647 Anti-Mouse CD1d Antibody [19G11] (AGEL0151)

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SKU:
AGEL0151
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Mouse
Host Species:
Rat
Isotype:
IgG2b
Clone:
19G11
Conjugation:
AF 647
Applications:
FC
Frequently bought together:

Description

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GenieFluor 647 Anti-Mouse CD1d Antibody [19G11]

The Mouse CD1d Monoclonal Antibody (Alexa Fluor 647 Conjugated, 19G11) is a powerful tool for research applications involving CD1d, a key molecule in the presentation of lipid antigens to natural killer T (NKT) cells. This monoclonal antibody, carefully developed for specificity and sensitivity, is ideal for flow cytometry and immunofluorescence studies in mouse models.CD1d is essential for the activation and regulation of NKT cells, which play a crucial role in bridging innate and adaptive immunity. By targeting CD1d with this antibody, researchers can explore the interactions between lipid antigens, CD1d, and NKT cells in various immune responses, including host defense, autoimmune diseases, and tumor immunity.

The high-quality conjugation of Alexa Fluor 647 enhances detection and imaging capabilities, facilitating precise localization and quantification of CD1d expression in different tissues and experimental conditions.With its reliability and versatility, the Mouse CD1d Monoclonal Antibody (Alexa Fluor 647 Conjugated, 19G11) is a valuable asset for studies aiming to unravel the intricate mechanisms of immune surveillance, tolerance, and pathogenesis, ultimately contributing to advancements in immunology, infectious diseases, and therapeutic interventions.

Product Title:GenieFluor 647 Anti-Mouse CD1d Antibody [19G11]
SKU:AGEL0151
Size:50 Tests, 100 Tests, 200 Tests
Clone No:19G11
Synonyms:Antigen-presenting glycoprotein CD1d1;Cd1d1;CD1d.1;Cd1d1;Cd1.1;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2b, κ
Isotype Control:Genie Fluor 647 Rat IgG2b, κ Isotype Control[LTF-2]
Form:Liquid
Conjugation:Genie Fluor647
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P11609
Gene ID:12479
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD1d is a type I transmembrane protein and member of the MHC family, with a molecular weight ranging from 43-49 kD, depending on the glycosylation degree. CD1d is expressed by antigen presenting cells such as dendritic cells, monocytes, macrophages and B cells; also expressed by thymocytes and intestinal epithelial cells. CD1d present glycolipids to iNKT cells that recognize them by their Vα14i TCR.

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