The ANRTI Mouse CD11a Monoclonal Antibody (Alexa Fluor 647 Conjugated) is a powerful tool for research involving CD11a, a key cell surface molecule involved in immune regulation and cell adhesion processes. This monoclonal antibody, recognized as FD441-8 (AGEL0158) by Assay Genie, is specifically designed for use in immunofluorescence and flow cytometry applications. It binds to the CD11a antigen with high specificity and sensitivity, enabling precise detection and analysis of CD11a expression on various cell types.CD11a, also known as integrin alpha L, plays a crucial role in immune cell trafficking, activation, and interactions within the immune system. Its involvement in inflammatory responses and immune surveillance makes it a significant target for research in immunology, inflammation, and autoimmune diseases.
By utilizing the ANRTI Mouse CD11a Monoclonal Antibody, researchers can gain insights into the functions of CD11a in different biological contexts, aiding in the development of targeted therapies for immune-related disorders and conditions.Overall, the ANRTI Mouse CD11a Monoclonal Antibody offers researchers a reliable tool for investigating the roles of CD11a in immune responses, inflammation, and immune cell adhesion processes, contributing to advancements in understanding immune system regulation and therapeutic development.
Integrin alpha-L;Itgal;CD11 antigen-like family member A;LFA-1A;Lymphocyte antigen 15;Ly-15;CD11a;
Host Species:
Rat
Reactivity:
Mouse
Application:
FCM
Isotype:
Rat IgG2b, κ
Isotype Control:
Genie Fluor 647 Rat IgG2b, κ Isotype Control[LTF-2]
Form:
Liquid
Conjugation:
Genie Fluor647
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P24063
Gene ID:
16408
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD11a is a 180 kD glycoprotein, also known as αL integrin, LFA-1 α, Ly-15, or Ly-21. It is a member of the integrin family, primarily expressed on lymphocytes, monocytes/macrophages, and granulocytes. In association with CD18, the CD11a/CD18 complex forms LFA-1. CD11a plays an important role in intercellular adhesion and costimulation by binding its ligands, ICAM-1 (CD54), ICAM-2 (CD102), and ICAM-3 (CD50).