AMBP Antibody (PACO15400)
- SKU:
- PACO15400
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
| Antibody Name: | AMBP Antibody (PACO15400) |
| Antibody SKU: | PACO15400 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:5000, IHC:1:25-1:100 |
| Species Reactivity: | Human |
| Immunogen: | Fusion protein of human AMBP |
| Form: | Liquid |
| Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Purification Method: | Antigen affinity purification |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using PACO15400(AMBP Antibody) at dilution 1/35, on the right is treated with fusion protein. (Original magnification: x200). |
 | The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using PACO15400(AMBP Antibody) at dilution 1/35, on the right is treated with fusion protein. (Original magnification: x200). |
| Background: | This gene encodes a complex glycoprotein secreted in plasma. The precursor is proteolytically processed into distinct functioning proteins: alpha-1-microglobulin, which belongs to the superfamily of lipocalin transport proteins and may play a role in the regulation of inflammatory processes, and bikunin, which is a urinary trypsin inhibitor belonging to the superfamily of Kunitz-type protease inhibitors and plays an important role in many physiological and pathological processes. This gene is located on chromosome 9 in a cluster of lipocalin genes. |
| Synonyms: | alpha-1-microglobulin/bikunin precursor |
| UniProt Protein Function: | AMBP: Inter-alpha-trypsin inhibitor inhibits trypsin, plasmin, and lysosomal granulocytic elastase. Inhibits calcium oxalate crystallization. |
| UniProt Protein Details: | Protein type:Secreted, signal peptide; Secreted Chromosomal Location of Human Ortholog: 9q32-q33 Cellular Component: extracellular space; cell surface; intracellular membrane-bound organelle; plasma membrane; extracellular region Molecular Function:serine-type endopeptidase inhibitor activity; protein binding; protein homodimerization activity; calcium oxalate binding; IgA binding; heme binding; calcium channel inhibitor activity Biological Process: negative regulation of JNK cascade; receptor-mediated endocytosis; viral reproduction; heme catabolic process; negative regulation of immune response; protein catabolic process; female pregnancy; cell adhesion; protein-chromophore linkage |
| NCBI Summary: | This gene encodes a complex glycoprotein secreted in plasma. The precursor is proteolytically processed into distinct functioning proteins: alpha-1-microglobulin, which belongs to the superfamily of lipocalin transport proteins and may play a role in the regulation of inflammatory processes, and bikunin, which is a urinary trypsin inhibitor belonging to the superfamily of Kunitz-type protease inhibitors and plays an important role in many physiological and pathological processes. This gene is located on chromosome 9 in a cluster of lipocalin genes. [provided by RefSeq, Jul 2008] |
| UniProt Code: | P02760 |
| NCBI GenInfo Identifier: | 122801 |
| NCBI Gene ID: | 259 |
| NCBI Accession: | P02760.1 |
| UniProt Related Accession: | P02760 |
| Molecular Weight: | |
| NCBI Full Name: | Protein AMBP |
| NCBI Synonym Full Names: | alpha-1-microglobulin/bikunin precursor |
| NCBI Official Symbol: | AMBP |
| NCBI Official Synonym Symbols: | A1M; HCP; ITI; UTI; EDC1; HI30; ITIL; IATIL; ITILC |
| NCBI Protein Information: | protein AMBP |
| UniProt Protein Name: | Protein AMBP |
| UniProt Synonym Protein Names: | Alpha-1 microglycoprotein; Complex-forming glycoprotein heterogeneous in charge |
| Protein Family: | Alpha-1-macroglobulin |
| UniProt Gene Name: | AMBP |
| UniProt Entry Name: | AMBP_HUMAN |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
Related Products
Human Protein AMBP (AMBP) ELISA Kit
Mouse Protein AMBP (Ambp) ELISA Kit
