ALOX15 Antibody (PACO19272)
제품 코드를 사용하여 Assay Genie 메인 사이트를 통해 주문합니다.
주문- SKU:
- PACO19272
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Description
Antibody Name: | ALOX15 Antibody (PACO19272) |
Antibody SKU: | PACO19272 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC |
Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:1000-1:5000, IHC:1:50-1:200 |
Species Reactivity: | Human, Mouse, Rat |
Immunogen: | Synthetic peptide of human ALOX15 |
Form: | Liquid |
Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Purification Method: | Antigen affinity purification |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
![]() | The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using PACO19272(ALOX15 Antibody) at dilution 1/60, on the right is treated with synthetic peptide. (Original magnification: x200). |
![]() | Gel: 10%SDS-PAGE, Lysate: 40 μg, Lane: Hela cells, Primary antibody: PACO19272(ALOX15 Antibody) at dilution 1/1300, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute. |
![]() | The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using PACO19272(ALOX15 Antibody) at dilution 1/60, on the right is treated with synthetic peptide. (Original magnification: x200). |
Background: | Arachidonate 15-lipoxygenase is an enzyme that in humans is encoded by the ALOX15 gene. The ALOX15 gene maps to 17p13.3 in close proximity to the tumor-suppressor gene TP53. The ALOX15 gene product is implicated in antiinflammation, membrane remodeling, and cancer development/metastasis. Converts arachidonic acid, to 15S-hydroperoxyeicosatetraenoic acid, Also acts on C-12 of arachidonate as well as on linoleic acid, |
Synonyms: | arachidonate 15-lipoxygenase |
UniProt Protein Function: | ALOX15: Converts arachidonic acid to 15S- hydroperoxyeicosatetraenoic acid. Also acts on C-12 of arachidonate as well as on linoleic acid. Belongs to the lipoxygenase family. |
UniProt Protein Details: | Protein type:Motility/polarity/chemotaxis; EC 1.13.11.33; Oxidoreductase; Lipid Metabolism - linoleic acid; Lipid Metabolism - arachidonic acid; EC 1.13.11.31 Chromosomal Location of Human Ortholog: 17p13.3 Cellular Component: cytosol; extrinsic to internal side of plasma membrane; lipid particle; membrane; plasma membrane Molecular Function:arachidonate 12-lipoxygenase activity; arachidonate 15-lipoxygenase activity; iron ion binding; phosphatidylinositol-4,5-bisphosphate binding; protein binding Biological Process: apoptotic cell clearance; arachidonic acid metabolic process; bone mineralization; hepoxilin biosynthetic process; inflammatory response; leukotriene metabolic process; lipoxygenase pathway; negative regulation of adaptive immune response; ossification; phosphatidylethanolamine biosynthetic process; positive regulation of actin filament polymerization; wound healing |
UniProt Code: | P16050 |
NCBI GenInfo Identifier: | 126396 |
NCBI Gene ID: | 246 |
NCBI Accession: | P16050.3 |
UniProt Secondary Accession: | P16050,Q8N6R7, Q99657, A8K2P4, B7ZA11, |
UniProt Related Accession: | P16050 |
Molecular Weight: | 70,108 Da |
NCBI Full Name: | Arachidonate 15-lipoxygenase |
NCBI Synonym Full Names: | arachidonate 15-lipoxygenase |
NCBI Official Symbol: | ALOX15 |
NCBI Official Synonym Symbols: | 12-LOX; 15LOX-1; 15-LOX-1 |
NCBI Protein Information: | arachidonate 15-lipoxygenase |
UniProt Protein Name: | Arachidonate 15-lipoxygenase |
UniProt Synonym Protein Names: | 12/15-lipoxygenase; Arachidonate 12-lipoxygenase, leukocyte-type (EC:1.13.11.31 |
UniProt Gene Name: | ALOX15 |
UniProt Entry Name: | LOX15_HUMAN |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
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Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |