The TER-119 Monoclonal Antibody (AGEL1564) is a vital tool for researchers investigating erythroid lineage differentiation and maturation. This purified mouse monoclonal antibody is specifically designed to target the TER-119 antigen, which is highly expressed on erythroid cells during their terminal differentiation stages. TER-119 is a well-characterized marker that plays a crucial role in identifying and studying erythroid precursors, making this antibody essential for various research applications such as flow cytometry, immunohistochemistry, and cell sorting.
Its high specificity and sensitivity ensure reliable detection and analysis of TER-119-expressing cells in complex biological samples.By utilizing the TER-119 Monoclonal Antibody (AGEL1564), researchers can gain valuable insights into erythropoiesis, hematopoiesis, and erythroid cell populations in both normal and pathological conditions. This antibody is a valuable asset for studies exploring hematological disorders, erythroid differentiation mechanisms, and potential therapeutic targets related to red blood cell development.
AF/LE Purified Rat IgG2b, κ Isotype Control[LTF-2]
Form:
Liquid
Conjugation:
None (AF/LE)
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.25 µg per 106 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Gene ID:
104231
Storage Buffer:
0.2 μm filtered in PBS, pH 7.2. Azide Free (AF)/Low Endotoxin (LE): Contains no stabilizers or stabilizers. Endotoxin level is < 2 EU/mg as Determined by LAL gel clotting assay.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
The TER-119 antigen is a 52 kD glycophorin A-associated protein, also known as Ly-76. TER-119 is an erythroid-specific antigen expressed on early proerythroblasts to mature erythrocytes, but not on erythroid colony-forming cells (BFU-E, blast-forming unit erythroid, or CFU-E, colony-forming unit erythroid).