The AF-LE Purified Mouse Ly6C Monoclonal Antibody (MONTS-1) is a versatile tool for researchers investigating Ly6C, a protein marker associated with immune cell populations, inflammation, and immune responses. This monoclonal antibody, derived from mouse hybridoma cells, exhibits high specificity and sensitivity for Ly6C detection across various experimental settings.Ly6C, a member of the Ly6 family of proteins, serves as a prominent marker for distinguishing and characterizing specific immune cell subsets, particularly in the context of inflammation and immune regulation. Its differential expression on immune cells enables researchers to identify and track distinct populations involved in various physiological and pathological processes.
This antibody's purification process ensures optimal performance in techniques such as flow cytometry, immunohistochemistry, and immunoassays, allowing for precise and reliable detection of Ly6C in different biological samples. By targeting Ly6C, researchers can gain valuable insights into immune cell dynamics, immune responses, and the roles of specific cell populations in health and disease.With its ability to accurately detect and analyze Ly6C-expressing cells, the AF-LE Purified Mouse Ly6C Monoclonal Antibody (MONTS-1) is an invaluable asset for studies focused on immunology, inflammation, cancer biology, and other research areas where understanding immune cell phenotypes and functions is essential.
Lymphocyte antigen 6 complex; locus C;Ly 6C;Ly6c1;Ly6c2;
Host Species:
Rat
Reactivity:
Mouse
Application:
FCM;Depletion
Isotype:
Rat IgG2a, κ
Isotype Control:
AF/LE Purified Rat IgG2a, κ Isotype Control[2A3]
Form:
Liquid
Conjugation:
None (AF/LE)
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 106 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Swissprot:
P0CW03
Gene ID:
17067
Storage Buffer:
0.2 μm filtered in PBS, pH 7.2. Azide Free (AF)/Low Endotoxin (LE): Contains no stabilizers or stabilizers. Endotoxin level is < 2 EU/mg as Determined by LAL gel clotting assay.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
Most hematopoietic cells express one or more members of Ly-6 family. The expression of Ly-6 varies with development stage and activation. Ly-6C is a 14-17 kD GPI-linked surface protein expressed on mouse monocyte/macrophage cells, endothelial cells, neutrophils, and some T cell subsets. Ly-6C is reported to be an indicator of memory CD8+ T cells.