Low Endotoxin Purified Anti-Mouse IL-6 Antibody [MP5-20F3] (AGEL2070)

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SKU:
AGEL2070
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Mouse
Applications:
FC
Frequently bought together:

Description

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Low Endotoxin Purified Anti-Mouse IL-6 Antibody [MP5-20F3]

The Purified Mouse IL-6 Monoclonal Antibody (MP5-20F3) is a specialized tool for researchers studying interleukin-6 (IL-6), a key cytokine involved in inflammatory responses and immune regulation. This monoclonal antibody, derived from mouse sources, exhibits high specificity and sensitivity in binding to IL-6, enabling precise detection and quantification in various experimental settings.IL-6 is a multifunctional cytokine with diverse roles in immune responses, inflammation, and hematopoiesis. Its dysregulation has been implicated in various diseases, including autoimmune disorders, cancer, and chronic inflammatory conditions.

The ability to accurately measure IL-6 levels is crucial for understanding its impact on disease pathogenesis and for evaluating potential therapeutic strategies.The MP5-20F3 antibody is validated for use in techniques such as ELISA, Western blotting, and immunohistochemistry, providing researchers with a versatile tool for investigating the role of IL-6 in different biological systems. With its high specificity and reliable performance, this monoclonal antibody is an essential component for studies aiming to elucidate the complex functions of IL-6 in health and disease.

Product Title:Low Endotoxin Purified Anti-Mouse IL-6 Antibody [MP5-20F3]
SKU:AGEL2070
Size:50µg, 500µg, 1mg
Clone No:MP5-20F3
Synonyms:Interleukin-6;IL-6;B-cell hybridoma growth factor;Interleukin HP-1;
Host Species:Rat
Reactivity:Mouse
Application:ICFCM;Neut
Isotype:Rat IgG1, κ
Isotype Control:AF/LE Purified Rat IgG1, κ Isotype Control[HRPN]
Form:Liquid
Conjugation:None (AF/LE)
Recommended Use:Each lot of this antibody is quality control tested by ELISA assay. For ELISA applications, a concentration range of 0.5 – 2.0 µg/mL is recommended. To obtain a linear standard curve, serial dilutions of mouse IL-6 recombinant protein ranging from 500 to 8 pg/mL are recommended for each ELISA plate. For ELISPOT applications, a concentration range of 4.0 - 8.0 µg/mL is recommended. It is recommended that the reagent be titrated for optimal performance for each application.
Swissprot:P08505
Gene ID:16193
Storage Buffer:0.2 μm filtered in PBS, pH 7.2. Azide Free (AF)/Low Endotoxin (LE): Contains no stabilizers or stabilizers. Endotoxin level is < 2 EU/mg as Determined by LAL gel clotting assay.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:IL-6 is a potent lymphoid cell growth factor that stimulates the growth and survivability of certain B cells and T cells. IL-6 plays a role in host defense, acute phase reactions, immune responses, and hematopoiesis. IL-6 is expressed by T cells, B cells, monocytes, fibroblasts, hepatocytes, endothelial cells and keratinocytes.

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