The AF-le Purified Mouse IL-4 Monoclonal Antibody (11B11) from Assay Genie (AGEL2057) is a highly specific and reliable tool for researchers studying interleukin-4 (IL-4) signaling pathways and functions. This monoclonal antibody, generated from mouse cells, has been purified to ensure maximum efficiency in detection and analysis of IL-4 protein expression and activity.IL-4 is a multifunctional cytokine known for its role in regulating immune responses, particularly in promoting T helper 2 (Th2) cell differentiation and mediating anti-inflammatory effects. The 11B11 monoclonal antibody targets IL-4 with high affinity, allowing for precise detection and quantification of IL-4 levels in various biological samples.
This makes it an essential reagent for studies related to immunology, allergy, asthma, and infectious diseases.By using the AF-le Purified Mouse IL-4 Monoclonal Antibody (11B11), researchers can gain valuable insights into the mechanisms underlying IL-4-mediated immune responses and potentially uncover new therapeutic targets for conditions involving dysregulated IL-4 signaling. Whether investigating basic immunology processes or developing novel treatments, this antibody provides a critical tool for advancing research in the field of cytokine biology.
Each lot of this antibody is quality control tested by ELISA assay. For ELISPOT applications, a concentration range of 2-6 μg/ml is recommended. For ELISA capture applications, a concentration range of 0.5-2.0 μg/ml is recommended. To obtain a linear standard curve, serial dilutions of IL-4 recombinant protein ranging from 250 to 2 pg/ml are recommended for each ELISA plate. It is recommended that the reagent be titrated for optimal performance for each application.
Swissprot:
P07750
Gene ID:
16189
Storage Buffer:
0.2 μm filtered in PBS, pH 7.2. Azide Free (AF)/Low Endotoxin (LE): Contains no stabilizers or stabilizers. Endotoxin level is < 2 EU/mg as Determined by LAL gel clotting assay.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
IL-4 is a pleiotropic cytokine produced by activated T cells, mast cells, and basophils. IL-4 is a potent lymphoid cell growth factor which stimulates the growth and activation of certain B cells and T cells. IL-4 is important for regulation of T helper subset development.