Low Endotoxin Purified Anti-Mouse IL-2 Antibody [JES6-5H4] (AGEL2044)

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SKU:
AGEL2044
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Mouse
Applications:
FC
Frequently bought together:

Description

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Low Endotoxin Purified Anti-Mouse IL-2 Antibody [JES6-5H4]

The AF LE Purified Mouse IL-2 Monoclonal Antibody (JES6-5H4) (AGEL2044) is a specialized tool for researchers studying interleukin-2 (IL-2), a key cytokine involved in immune regulation and cell signaling. This monoclonal antibody, derived from mouse sources, offers high specificity and sensitivity in detecting IL-2 in various biological samples. Validated for use in immunofluorescence and flow cytometry applications, the JES6-5H4 antibody provides reliable data for investigating IL-2 expression and localization in experimental settings.IL-2 is a crucial signaling molecule in the immune system, playing a pivotal role in T cell activation, proliferation, and differentiation.

Dysregulation of IL-2 production or signaling is associated with a variety of immune disorders, including autoimmune diseases, allergies, and immunodeficiencies. By targeting IL-2 using antibodies like JES6-5H4, researchers can gain insights into the complex interplay of cytokine-mediated responses in health and disease. This antibody serves as a valuable tool for studies focused on immunology, cancer biology, and therapeutic interventions aimed at modulating immune responses.

Product Title:Low Endotoxin Purified Anti-Mouse IL-2 Antibody [JES6-5H4]
SKU:AGEL2044
Size:50µg, 500µg, 1mg
Clone No:JES6-5H4
Synonyms:Interleukin-2;IL-2;T-cell growth factor;TCGF;IL2;
Host Species:Rat
Reactivity:Mouse
Application:ICFCM;Neut;Stim
Isotype:Rat IgG2b, κ
Isotype Control:AF/LE Purified Rat IgG2b, κ Isotype Control[LTF-2]
Form:Liquid
Conjugation:None (AF/LE)
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 106 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Swissprot:P04351
Gene ID:16183
Storage Buffer:0.2 μm filtered in PBS, pH 7.2. Azide Free (AF)/Low Endotoxin (LE): Contains no stabilizers or stabilizers. Endotoxin level is < 2 EU/mg as Determined by LAL gel clotting assay.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:IL-2 is a potent lymphoid cell growth factor which exerts its biological activity primarily on T cells. Additionally, IL-2 has been found to stimulate growth and differentiation of B cells, NK cells, LAK cells, monocytes, and oligodendrocytes.

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