Low Endotoxin Purified Anti-Mouse CD38 Antibody [NIMR5] (AGEL2009)

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SKU:
AGEL2009
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Mouse
Applications:
FC
Frequently bought together:

Description

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Low Endotoxin Purified Anti-Mouse CD38 Antibody [NIMR5]

The Mouse CD38 Monoclonal Antibody (NIMR5) is a purified antibody designed for research involving CD38, a cell surface glycoprotein known for its role in immune regulation and cell signaling. This mouse monoclonal antibody, clone NIMR5, specifically targets and binds to the CD38 protein, allowing for precise detection and analysis in various cell types and tissues.CD38 is a multifunctional molecule involved in calcium signaling, cell adhesion, and immune response modulation. Its expression has been implicated in conditions such as cancer, inflammation, and autoimmune diseases, making it a valuable target for research in immunology and oncology.

This monoclonal antibody offers high specificity and sensitivity, making it an excellent tool for studying the function and expression of CD38 in different experimental settings.Researchers studying immune regulation, cell signaling, or diseases related to CD38 expression can benefit from the versatility and reliability of the Mouse CD38 Monoclonal Antibody (NIMR5). With its research-grade purity and validation for various applications, including immunohistochemistry and flow cytometry, this antibody provides valuable insights into the role of CD38 in health and disease.

Product Title:Low Endotoxin Purified Anti-Mouse CD38 Antibody [NIMR5]
SKU:AGEL2009
Size:50µg, 500µg, 1mg
Clone No:NIMR5
Synonyms:ADP-ribosyl cyclase 1;ADPRC 1;CD38;NIM-R5 antigen;2'-phospho-cyclic-ADP-ribose transferase;
Host Species:Rat
Reactivity:Mouse
Application:FCM;Activ;Stim;ELISA
Isotype:Rat IgG2a, κ
Isotype Control:AF/LE Purified Rat IgG2a, κ Isotype Control[2A3]
Form:Liquid
Conjugation:None (AF/LE)
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 2.0 µg per 106 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Swissprot:P56528
Gene ID:12494
Storage Buffer:0.2 μm filtered in PBS, pH 7.2. Azide Free (AF)/Low Endotoxin (LE): Contains no stabilizers or stabilizers. Endotoxin level is < 2 EU/mg as Determined by LAL gel clotting assay.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD38 is a 42 kD glycoprotein, also known as T10. It is an ADP-ribosyl hydrolase, expressed on B cells, NK cells, a subset of T cells, brain, muscle, and kidney. In mouse, CD38 expression is downregulated on germinal center B cells and plasma cells, whereas this is not the case for humans. By functioning as both a cyclase and a hydrolase, CD38 mediates lymphocyte activation, as well as adhesion and metabolism of cADPR and NAADP. CD31 is the ligand of CD38.

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