The Purified Mouse CD28 Monoclonal Antibody (37-51) (AGEL0759) offered by AssayGenie is a high-quality antibody designed for research applications involving CD28, a crucial co-stimulatory molecule in T cell activation. This monoclonal antibody, specifically targeting the CD28 protein in mice, is ideal for studying immune responses and T cell activation mechanisms.CD28 is essential for T cell activation and proliferation, playing a pivotal role in regulating immune responses. The purified mouse CD28 monoclonal antibody (37-51) (AGEL0759) is rigorously validated for its specificity and sensitivity in various experimental settings, such as flow cytometry and immunohistochemistry.
By targeting the CD28 protein, researchers can effectively investigate T cell activation pathways and unravel the complexities of immune regulation.This antibody's superior quality and specificity make it a valuable tool for studying immune responses, infectious diseases, and autoimmune disorders in preclinical research. With its reliable performance and accurate detection of CD28, the purified mouse CD28 monoclonal antibody (37-51) (AGEL0759) from AssayGenie is an essential reagent for researchers seeking to deepen their understanding of T cell biology and immune system function.
Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 106 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Swissprot:
P31041
Gene ID:
12487
Storage Buffer:
0.2 μm filtered in PBS, pH 7.2. Azide Free (AF)/Low Endotoxin (LE): Contains no stabilizers or stabilizers. Endotoxin level is < 2 EU/mg as Determined by LAL gel clotting assay.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD28 is a 44 kD glycoprotein, also known as Tp44 or T44. It is a member of the Ig superfamily, expressed on thymocytes, most peripheral T cells, and NK cells. In association with CD80 (B7-1) and CD86 (B7-2), CD28 acts as the second signal for T and NK cell activation and proliferation. The 37.51 antibody has been reported to augment in vitro T cell proliferation and cytokine production, and promote CTL development.
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