The Mouse CD19 Monoclonal Antibody (1D3), available through AssayGenie (AGEL0465), is a purified antibody specifically designed for research applications involving the CD19 protein. This antibody, generated in mice, exhibits high reactivity with mouse CD19, making it a reliable tool for various experimental techniques.CD19 is a cell surface marker commonly found on B cells and is crucial for B cell development and function. The 1D3 monoclonal antibody precisely targets the CD19 protein, facilitating its detection and analysis in different cell types and tissues. This feature makes it an excellent choice for studies focusing on B cell biology, immunology, and related areas.With its ability to bind specifically to CD19, the 1D3 monoclonal antibody opens up avenues for investigating B cell-related diseases, immune responses, and therapeutic interventions.
Researchers can utilize this antibody in techniques such as flow cytometry, immunohistochemistry, and western blotting to gain insights into CD19 expression patterns and functions in various biological contexts.Overall, the Mouse CD19 Monoclonal Antibody (1D3) from AssayGenie offers researchers a valuable tool to advance their studies in immunology, B cell biology, and diseases where CD19 plays a significant role. Its specificity and reliability make it an indispensable resource for those exploring B cell function, immune responses, and targeted therapies.
Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 106 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Swissprot:
P25918
Gene ID:
12478
Storage Buffer:
0.2 μm filtered in PBS, pH 7.2. Azide Free (AF)/Low Endotoxin (LE): Contains no stabilizers or stabilizers. Endotoxin level is < 2 EU/mg as Determined by LAL gel clotting assay.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD19 is a 95 kD glycoprotein also known as B4. It is a member of the Ig superfamily, expressed on all pro-B to mature B cells (during development) and follicular dendritic cells. Plasma cells do not express CD19. CD19, in association with CD21 and CD81, forms a molecular complex integral to B cell activation.