The AF-Le Purified Human IL-4 Monoclonal Antibody (MP4-25D2) from AssayGenie (AGEL2053) is a powerful tool for researchers studying interleukin-4 (IL-4), a cytokine involved in immune responses and inflammatory processes. This monoclonal antibody is specifically designed to target and detect human IL-4 in various experimental settings.IL-4 is a crucial signaling molecule that plays a key role in regulating immune responses, particularly in the context of allergies, autoimmune diseases, and infectious conditions. By targeting IL-4, researchers can gain valuable insights into the mechanisms underlying these diseases and potential therapeutic targets for intervention.The AF-Le Purified Human IL-4 Monoclonal Antibody (MP4-25D2) is rigorously tested and validated for use in a range of applications, including Western blotting, ELISA, immunofluorescence, and flow cytometry.
Its high specificity and sensitivity make it an essential tool for elucidating the role of IL-4 in various biological processes.For researchers looking to delve deeper into the intricacies of immune regulation and inflammatory responses, the AF-Le Purified Human IL-4 Monoclonal Antibody (MP4-25D2) offers a reliable and precise solution for their experimental needs. Trust AssayGenie for high-quality antibodies that drive impactful discoveries in the field of immunology and beyond.
Each lot of this antibody is quality control tested by ELISA assay. Purified MP4-25D2 has been tested by blocking fluorochrome conjugated MP4-25D2 for intracellular cytokine staining. In order to obtain complete blocking results, a saturated amount of purified antibody (≤ 5.0 µg/million cells) should be used for incubation with target cells, prior to staining with fluorochrome conjugated antibody. It is recommended that the reagent be titrated for optimal performance for each application.
Swissprot:
P05112
Gene ID:
3565
Storage Buffer:
0.2 μm filtered in PBS, pH 7.2. Azide Free (AF)/Low Endotoxin (LE): Contains no stabilizers or stabilizers. Endotoxin level is < 2 EU/mg as Determined by LAL gel clotting assay.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
IL-4 is a pleiotropic cytokine that is produced by activated T cells, mast cells, and basophils. IL-4 elicits many different biological responses but has two dominant functions. The first is regulating differentiation of naïve CD4+ T cell to the Th2 type. Th2 cells produce IL-4, IL-5, IL-10, and IL-13, which tend to favor a humoral immune response while suppressing a cell-mediated immune response controlled by Th1 cells. The second is regulating IgE and IgG1 production by B cells.
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