Low Endotoxin Purified Anti-Human HLA-DR Antibody [L243] (AGEL1395)

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SKU:
AGEL1395
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Applications:
FC
Frequently bought together:

Description

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Low Endotoxin Purified Anti-Human HLA-DR Antibody [L243]

The Human HLA-DR Monoclonal Antibody (L243) is a highly specific antibody designed for research involving the human leukocyte antigen HLA-DR, an essential player in the immune system's recognition of foreign antigens. This monoclonal antibody, designated AGEL1395, is purified for enhanced performance and precision in various immunological studies.HLA-DR is a crucial component of the major histocompatibility complex (MHC) class II molecules, responsible for presenting antigens to immune cells to initiate an adaptive immune response. The L243 monoclonal antibody precisely targets the HLA-DR protein, allowing researchers to detect and characterize its expression and function in diverse cell types and experimental settings.

With applications in immunology, transplantation research, infectious diseases, and autoimmunity studies, the Human HLA-DR Monoclonal Antibody (L243) offers a valuable tool for investigating immune responses, antigen presentation, and immune-related disorders. Its high specificity and reliability make it an essential reagent for researchers aiming to unravel the complexities of the human immune system.

Product Title:Low Endotoxin Purified Anti-Human HLA-DR Antibody [L243]
SKU:AGEL1395
Size:50µg, 500µg, 1mg
Clone No:L243
Synonyms:HLA class II histocompatibility antigen DR alpha/ DRB1-15 beta chain;MHC class II antigen DRA;HLA-DRA1/DRB1;DRA/DRB1;
Host Species:Mouse
Reactivity:Human
Application:FCM;Cell Sep-Neg;Block;Binding
Isotype:Mouse IgG2a, κ
Isotype Control:AF/LE Purified Mouse IgG2a, κ Isotype Control[C1.18.4]
Form:Liquid
Conjugation:None (AF/LE)
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 2.0 µg per 106 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Swissprot:P01903 P01911
Gene ID:3122,3123
Storage Buffer:0.2 μm filtered in PBS, pH 7.2. Azide Free (AF)/Low Endotoxin (LE): Contains no stabilizers or stabilizers. Endotoxin level is < 2 EU/mg as Determined by LAL gel clotting assay.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:HLA-DR is a heterodimeric cell surface glycoprotein comprised of a 36 kD α (heavy) chain and a 27 kD β (light) chain. It is expressed on B cells, activated T cells, monocytes/macrophages, dendritic cells, and other non-professional APCs. In conjunction with the CD3/TCR complex and CD4 molecules, HLA-DR is critical for efficient peptide presentation to CD4+ T cells.

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