Low Endotoxin Purified Anti-Human CD40 Antibody [G28.5] (AGEL2094)

(No reviews yet) Write a Review
SKU:
AGEL2094
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Applications:
FC
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS

Low Endotoxin Purified Anti-Human CD40 Antibody [G28.5]

The Purified Human CD40 Monoclonal Antibody (G28-5) is a specialized research tool offered by Assay Genie for investigating the CD40 cell surface molecule. This monoclonal antibody, purified from human samples, exhibits high specificity and reactivity towards CD40, enabling precise detection and analysis in various experimental settings. Validated for use in diverse applications such as immunohistochemistry and flow cytometry, this antibody is a valuable asset for researchers exploring the role of CD40 in immune responses, inflammation, and disease pathology.CD40, a key cell surface receptor involved in immune regulation and activation, plays a crucial role in modulating B cell functions, antigen presentation, and cytokine production.

By targeting CD40, researchers can gain insight into immune signaling pathways, potential therapeutic targets for autoimmune diseases, and the development of novel immunotherapies. The Purified Human CD40 Monoclonal Antibody (G28-5) serves as an essential tool for probing the intricate functions of CD40 in various biological contexts, advancing our understanding of immune responses and paving the way for innovative biomedical research.

Product Title:Low Endotoxin Purified Anti-Human CD40 Antibody [G28.5]
SKU:AGEL2094
Size:50µg, 500µg, 1mg
Clone No:G28.5
Synonyms:Bp50;CDw40;CD40L receptor;TNFRSF5;
Host Species:Mouse
Reactivity:Human
Application:FCM;Stim;FA
Isotype:Mouse IgG1, κ
Isotype Control:AF/LE Purified Mouse IgG1, κ Isotype Control[MOPC-21]
Form:Liquid
Conjugation:None (AF/LE)
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 2.0 µg per 106 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Swissprot:P25942
Gene ID:958
Storage Buffer:0.2 μm filtered in PBS, pH 7.2. Azide Free (AF)/Low Endotoxin (LE): Contains no stabilizers or stabilizers. Endotoxin level is < 2 EU/mg as Determined by LAL gel clotting assay.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD40 is a 48 kD type I glycoprotein also known as BP50. It is a member of the TNFR superfamily primarily expressed on B cells, macrophages, follicular dendritic cells, endothelial cells, fibroblasts, and at low levels on plasma cells. CD40 has been reported to be involved in B cell differentiation, costimulation, isotype class-switching, and protection of B cells from apoptosis. Additionally, CD40 is important for T cell-B cell interactions. The ligand of CD40 is CD154 (CD40 ligand).

0 Reviews

View AllClose

Related Products