Low Endotoxin Purified Anti-Human CD3 Antibody [OKT-3] (AGEL0602)

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SKU:
AGEL0602
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Applications:
FC
Frequently bought together:

Description

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Low Endotoxin Purified Anti-Human CD3 Antibody [OKT-3]

The AF LE Purified Human CD3 Monoclonal Antibody (OKT3) - AGEL0602 is a high-quality antibody designed for research applications involving CD3, a crucial cell surface marker found on T cells. This monoclonal antibody has been purified and optimized for specificity and sensitivity in various assays, making it an excellent tool for immunological studies.CD3 is a co-receptor complex essential for T cell activation and function. By targeting CD3 specifically, this monoclonal antibody enables researchers to study T cell activation, differentiation, and function in both normal and pathological conditions. The antibody binds specifically to the CD3 antigen, allowing for precise detection and analysis in a variety of cell types and experimental settings.

Research involving CD3 is vital for understanding immune responses, T cell-mediated immunity, and the development of therapeutic interventions for conditions such as autoimmune diseases, infectious diseases, and cancer. The AF LE Purified Human CD3 Monoclonal Antibody (OKT3) - AGEL0602 offers reliable performance and consistent results in diverse research applications, making it an indispensable tool for scientists and researchers in the fields of immunology, oncology, and beyond.

Product Title:Low Endotoxin Purified Anti-Human CD3 Antibody [OKT-3]
SKU:AGEL0602
Size:50µg, 500µg, 1mg
Clone No:OKT-3
Synonyms:T-cell surface glycoprotein CD3 epsilon chain;CD3E;T-cell surface antigen T3/Leu-4 epsilon chain;CD3e;CD3E;T3E;
Host Species:Mouse
Reactivity:Human
Application:FCM;Activ;Depletion;Inhibition
Isotype:Mouse IgG2a, κ
Isotype Control:AF/LE Purified Mouse IgG2a, κ Isotype Control[C1.18.4]
Form:Liquid
Conjugation:None (AF/LE)
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.5 µg per 106 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Swissprot:P07766
Gene ID:916
Storage Buffer:0.2 μm filtered in PBS, pH 7.2. Azide Free (AF)/Low Endotoxin (LE): Contains no stabilizers or stabilizers. Endotoxin level is < 2 EU/mg as Determined by LAL gel clotting assay.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD3ε is a 20 kD chain of the CD3/T cell receptor (TCR) complex, which is composed of two CD3ε, one CD3γ, one CD3δ, one CD3ζ (CD247), and a T cell receptor (α/β or γ/δ) heterodimer. It is found on all mature T lymphocytes, NK T cells, and some thymocytes. CD3, also known as T3, is a member of the immunoglobulin superfamily that plays a role in antigen recognition, signal transduction, and T cell activation.

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