| UniProt Protein Function: | ABCA13: In human, the ATP-binding cassette (ABC) family of transmembrane transporters has at least 48 genes and 7 gene subfamilies. This gene is a member of ABC gene subfamily A (ABCA). Genes within the ABCA family typically encode several thousand amino acids. Like other ABC transmembrane transporter proteins, this protein has 12 or more transmembrane alpha-helix domains that likely arrange to form a single central chamber with multiple substrate binding sites. It is also predicted to have two large extracellular domains and two nucleotide binding domains as is typical for ABCA proteins. Alternative splice variants have been described but their biological validity has not been demonstrated.[provided by RefSeq, Mar 2009]Protein type: Membrane protein, multi-pass; Membrane protein, integralChromosomal Location of Human Ortholog: 7p12.3Cellular Component: integral to membraneMolecular Function: transporter activity; ATPase activity; ATP bindingBiological Process: transport; metabolic process |
| UniProt Protein Details: | |
| NCBI Summary: | In human, the ATP-binding cassette (ABC) family of transmembrane transporters has at least 48 genes and 7 gene subfamilies. This gene is a member of ABC gene subfamily A (ABCA). Genes within the ABCA family typically encode several thousand amino acids. Like other ABC transmembrane transporter proteins, this protein has 12 or more transmembrane alpha-helix domains that likely arrange to form a single central chamber with multiple substrate binding sites. It is also predicted to have two large extracellular domains and two nucleotide binding domains as is typical for ABCA proteins. Alternative splice variants have been described but their biological validity has not been demonstrated.[provided by RefSeq, Mar 2009] |
| UniProt Code: | Q86UQ4 |
| NCBI GenInfo Identifier: | 597709765 |
| NCBI Gene ID: | 154664 |
| NCBI Accession: | NP_689914.3 |
| UniProt Secondary Accession: | Q86UQ4,Q6ZTT7, Q86WI2, Q8N248, K9LC76, K9LC79, K9LCX7 K9LDK8, K9LDY4 |
| UniProt Related Accession: | Q86UQ4 |
| Molecular Weight: | 258,321 Da |
| NCBI Full Name: | ATP-binding cassette sub-family A member 13 |
| NCBI Synonym Full Names: | ATP-binding cassette, sub-family A (ABC1), member 13 |
| NCBI Official Symbol: | ABCA13 |
| NCBI Official Synonym Symbols: | |
| NCBI Protein Information: | ATP-binding cassette sub-family A member 13; ATP binding cassette transporter A13; ATP-binding cassette sub-family A member 13 variant 2; ATP-binding cassette sub-family A member 13 variant 3 |
| UniProt Protein Name: | ATP-binding cassette sub-family A member 13 |
| UniProt Synonym Protein Names: | |
| Protein Family: | ATP-binding cassette sub-family |
| UniProt Gene Name: | ABCA13 |
| UniProt Entry Name: | ABCAD_HUMAN |
