YEATS2 Antibody (PACO23497)
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주문- SKU:
- PACO23497
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | YEATS2 Antibody (PACO23497) |
Antibody SKU: | PACO23497 |
Size: | 100ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC |
Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:3000, IHC:1:50-1:100 |
Species Reactivity: | Human |
Immunogen: | Synthesized peptide derived from internal of human YEATS2. |
Form: | Liquid |
Storage Buffer: | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
![]() | Western blot analysis of extracts from 293 cells, using YEATS2 antiobdy. |
![]() | Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue using YEATS2 antibody. |
Background: | Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4. |
Synonyms: | YEATS domain-containing protein 2; YEATS2; KIAA1197; |
UniProt Protein Function: | Chromatin reader component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4. YEATS2 specifically recognizes and binds histone H3 crotonylated at 'Lys-27' (H3K27cr) (PubMed:27103431). Crotonylation marks active promoters and enhancers and confers resistance to transcriptional repressors (PubMed:27103431). |
NCBI Summary: | Summary: The protein encoded by this gene is a scaffolding subunit of the ATAC complex, which is a complex with acetyltransferase activity on histones H3 and H4. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, May 2017] |
UniProt Code: | Q9ULM3 |
NCBI GenInfo Identifier: | 33620755 |
NCBI Gene ID: | 55689 |
NCBI Accession: | NP_060493.3 |
UniProt Secondary Accession: | Q9ULM3,Q641P6, Q9NW96, A7E2B9, D3DNS9, |
UniProt Related Accession: | Q9ULM3 |
Molecular Weight: | 150,782 Da |
NCBI Full Name: | YEATS domain-containing protein 2 isoform 3 |
NCBI Synonym Full Names: | YEATS domain containing 2 |
NCBI Official Symbol: | YEATS2 |
NCBI Protein Information: | YEATS domain-containing protein 2 |
UniProt Protein Name: | YEATS domain-containing protein 2 |
Protein Family: | YEATS domain-containing protein |
UniProt Gene Name: | YEATS2 |