XPNPEP1 Antibody (PACO41394)
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주문- SKU:
- PACO41394
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | XPNPEP1 Antibody (PACO41394) |
Antibody SKU: | PACO41394 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC |
Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:1000-1:5000, IHC:1:20-1:200 |
Species Reactivity: | Human, Mouse |
Immunogen: | Recombinant Human Xaa-Pro aminopeptidase 1 protein (2-623AA) |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
Purification Method: | >95%, Protein G purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
![]() | Western blot. All lanes: Xaa-Pro aminopeptidase 1 antibody at 8µg/ml. Lane 1: Mouse small intestine tissue. Lane 2: Mouse stomach tissue. Lane 3: Mouse kidney tissue. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 70, 68, 75, 73 kDa. Observed band size: 70 kDa. |
![]() | Immunohistochemistry of paraffin-embedded human colon cancer using PACO41394 at dilution of 1:100. |
Background: | Contributes to the degradation of bradykinin. Catalyzes the removal of a penultimate prolyl residue from the N-termini of peptides, such as Arg-Pro-Pro. |
Synonyms: | Xaa-Pro aminopeptidase 1 (EC 3.4.11.9) (Aminoacylproline aminopeptidase) (Cytosolic aminopeptidase P) (Soluble aminopeptidase P) (sAmp) (X-Pro aminopeptidase 1) (X-prolyl aminopeptidase 1, soluble), XPNPEP1, XPNPEPL XPNPEPL1 |
UniProt Protein Function: | XPNPEP1: Contributes to the degradation of bradykinin. Catalyzes the removal of a penultimate prolyl residue from the N-termini of peptides, such as Arg-Pro-Pro. Belongs to the peptidase M24B family. 2 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:EC 3.4.11.9; Protease Chromosomal Location of Human Ortholog: 10q25.3 Cellular Component: cytoplasm Molecular Function:aminopeptidase activity; manganese ion binding; protein homodimerization activity Biological Process: proteolysis |
NCBI Summary: | This gene encodes the cytosolic form of a metalloaminopeptidase that catalyzes the cleavage of the N-terminal amino acid adjacent to a proline residue. The gene product may play a role in degradation and maturation of tachykinins, neuropeptides, and peptide hormones. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Nov 2009] |
UniProt Code: | Q9NQW7 |
NCBI GenInfo Identifier: | 264681565 |
NCBI Gene ID: | 7511 |
NCBI Accession: | NP_001161076.1 |
UniProt Related Accession: | Q9NQW7 |
Molecular Weight: | |
NCBI Full Name: | xaa-Pro aminopeptidase 1 isoform 2 |
NCBI Synonym Full Names: | X-prolyl aminopeptidase 1 |
NCBI Official Symbol: | XPNPEP1 |
NCBI Official Synonym Symbols: | APP1; SAMP; XPNPEP; XPNPEPL; XPNPEPL1 |
NCBI Protein Information: | xaa-Pro aminopeptidase 1 |
UniProt Protein Name: | Xaa-Pro aminopeptidase 1 |
UniProt Synonym Protein Names: | Aminoacylproline aminopeptidase; Cytosolic aminopeptidase P; Soluble aminopeptidase P; sAmp; X-Pro aminopeptidase 1; X-prolyl aminopeptidase 1, soluble |
UniProt Gene Name: | XPNPEP1 |
UniProt Entry Name: | XPP1_HUMAN |