WRB Antibody (PACO46326)
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주문- SKU:
- PACO46326
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Application:
- IF
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | WRB Antibody (PACO46326) |
Antibody SKU: | PACO46326 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC, IF |
Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:2000-1:5000, IHC:1:20-1:200, IF:1:50-1:200 |
Species Reactivity: | Human, Mouse |
Immunogen: | Recombinant Human Tail-anchored protein insertion receptor WRB protein (38-99AA) |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
Purification Method: | >95%, Protein G purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Western Blot. Positive WB detected in: Mouse spleen tissue. All lanes: WRB antibody at 3.4ug/ml. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 20, 17 kDa. Observed band size: 20 kDa.. | |
Immunofluorescent analysis of Hela cells using PACO46326 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). | |
Immunohistochemistry of paraffin-embedded human testis tissue using PACO46326 at dilution of 1:100. |
Background: | Receptor for ASNA1/TRC40-mediated insertion of tail-anchored (TA) proteins into the ER membrane. |
Synonyms: | Tail-anchored protein insertion receptor WRB (Congenital heart disease 5 protein) (Tryptophan-rich basic protein) (WRB), WRB, CHD5 |
UniProt Protein Function: | WRB: Receptor for ASNA1/TRC40-mediated insertion of tail- anchored (TA) proteins into the ER membrane. Belongs to the WRB/GET1 family. 2 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Membrane protein, multi-pass; Membrane protein, integral Chromosomal Location of Human Ortholog: 21q22.3 Cellular Component: endoplasmic reticulum membrane; integral to membrane; nucleus |
NCBI Summary: | This gene encodes a basic nuclear protein of unknown function. The gene is widely expressed in adult and fetal tissues. Since the region proposed to contain the gene(s) for congenital heart disease (CHD) in Down syndrome (DS) patients has been restricted to 21q22.2-22.3, this gene, which maps to 21q22.3, has a potential role in the pathogenesis of Down syndrome congenital heart disease. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2009] |
UniProt Code: | O00258 |
NCBI GenInfo Identifier: | 12643986 |
NCBI Gene ID: | 7485 |
NCBI Accession: | O00258.2 |
UniProt Secondary Accession: | O00258,O60740, A8KAP8, A8MQ44, D3DSH9, |
UniProt Related Accession: | O00258 |
Molecular Weight: | 174 |
NCBI Full Name: | Tail-anchored protein insertion receptor WRB |
NCBI Synonym Full Names: | tryptophan rich basic protein |
NCBI Official Symbol: | WRB |
NCBI Official Synonym Symbols: | CHD5 |
NCBI Protein Information: | tail-anchored protein insertion receptor WRB; tryptophan-rich protein; tryptophan-rich basic protein; congenital heart disease 5 protein |
UniProt Protein Name: | Tail-anchored protein insertion receptor WRB |
UniProt Synonym Protein Names: | Congenital heart disease 5 protein; Tryptophan-rich basic protein; WRB |
Protein Family: | Tail-anchored protein insertion receptor |
UniProt Gene Name: | WRB |
UniProt Entry Name: | WRB_HUMAN |
Antibodies | ELISA Kits |
Anti-WRB Antibody (CAB7000) | Human CHD5 / Chromodomain Helicase DNA Binding Protein 5 ELISA Kit |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |