WLS Antibody (PACO57184)
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주문- SKU:
- PACO57184
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | WLS Antibody (PACO57184) |
Antibody SKU: | PACO57184 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC |
Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:5000, IHC:1:200-1:500 |
Species Reactivity: | Human |
Immunogen: | Recombinant Human Protein wntless homolog protein (123-232AA) |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
Purification Method: | >95%, Protein G purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
![]() | Western Blot. Positive WB detected in: HepG2 whole cell lysate. All lanes: WLS antibody at 5.4µg/ml. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 63, 52 kDa. Observed band size: 52 kDa. |
![]() | IHC image of PACO57184 diluted at 1:200 and staining in paraffin-embedded human adrenal gland tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system. |
![]() | IHC image of PACO57184 diluted at 1:200 and staining in paraffin-embedded human kidney tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system. |
Background: | Regulates Wnt proteins sorting and secretion in a feedback regulatory mechanism. This reciprocal interaction plays a key role in the regulation of expression, subcellular location, binding and organelle-specific association of Wnt proteins. Plays also an important role in establishment of the anterior-posterior body axis formation during development (By similarity). |
Synonyms: | Protein wntless homolog (Integral membrane protein GPR177) (Protein evenness interrupted homolog) (EVI) (Putative NF-kappa-B-activating protein 373), WLS, C1orf139 GPR177 |
UniProt Protein Function: | Regulates Wnt proteins sorting and secretion in a feedback regulatory mechanism. This reciprocal interaction plays a key role in the regulation of expression, subcellular location, binding and organelle-specific association of Wnt proteins. Plays also an important role in establishment of the anterior-posterior body axis formation during development. |
UniProt Code: | Q5T9L3 |
NCBI GenInfo Identifier: | 301069320 |
NCBI Gene ID: | 79971 |
NCBI Accession: | NP_001002292.3 |
UniProt Secondary Accession: | Q5T9L3,Q5JRS7, Q7Z2Z9, Q8NC43, B2RNT2, |
UniProt Related Accession: | Q5T9L3 |
Molecular Weight: | 62 kDa |
NCBI Full Name: | protein wntless homolog isoform 2 |
NCBI Synonym Full Names: | Wnt ligand secretion mediator |
NCBI Official Symbol: | WLS |
NCBI Official Synonym Symbols: | EVI; MRP; GPR177; mig-14; C1orf139 |
NCBI Protein Information: | protein wntless homolog |
UniProt Protein Name: | Protein wntless homolog |
UniProt Synonym Protein Names: | Integral membrane protein GPR177; Protein evenness interrupted homolog; EVI; Putative NF-kappa-B-activating protein 373 |
Protein Family: | Protein wntless |
UniProt Gene Name: | WLS |