WASF3 Antibody (PACO02370)
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주문- SKU:
- PACO02370
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | WASF3 Antibody |
Antibody SKU: | PACO02370 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC |
Recommended Dilutions: | WB:1:500-1:2000, IHC:1:100-1:300 |
Species Reactivity: | Human, Mouse |
Immunogen: | synthesized peptide derived from the Internal region of human WAVE3. |
Form: | Liquid |
Storage Buffer: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Synonyms: | WASF3; KIAA0900; SCAR3; WAVE3; Wiskott-Aldrich syndrome protein family member 3; WASP family protein member 3; Protein WAVE-3; Verprolin homology domain-containing protein 3 |
UniProt Protein Function: | WASF3: Downstream effector molecules involved in the transmission of signals from tyrosine kinase receptors and small GTPases to the actin cytoskeleton. Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the control of cell shape. Binds actin and the Arp2/3 complex. Expressed in ovary and brain. Belongs to the SCAR/WAVE family. |
UniProt Protein Details: | Protein type:Actin-binding; Motility/polarity/chemotaxis Chromosomal Location of Human Ortholog: 13q12 Cellular Component: cytoskeleton; lamellipodium; cytoplasm Molecular Function:actin binding Biological Process: positive regulation of myelination; lamellipodium biogenesis; regulation of cell shape; actin filament polymerization; cytoskeleton organization and biogenesis; protein complex assembly; oligodendrocyte development |
NCBI Summary: | This gene encodes a member of the Wiskott-Aldrich syndrome protein family. The gene product is a protein that forms a multiprotein complex that links receptor kinases and actin. Binding to actin occurs through a C-terminal verprolin homology domain in all family members. The multiprotein complex serves to tranduce signals that involve changes in cell shape, motility or function. A pseudogene of this gene have been defined on chromosome 6. Alternative splicing results in multiple transcript variants [provided by RefSeq, May 2014] |
UniProt Code: | Q9UPY6 |
NCBI GenInfo Identifier: | 13699803 |
NCBI Gene ID: | 10810 |
NCBI Accession: | NP_006637.2 |
UniProt Secondary Accession: | Q9UPY6,O94974, Q86VQ2, |
UniProt Related Accession: | Q9UPY6 |
Molecular Weight: | 55,293 Da |
NCBI Full Name: | wiskott-Aldrich syndrome protein family member 3 isoform 1 |
NCBI Synonym Full Names: | WAS protein family, member 3 |
NCBI Official Symbol: | WASF3 |
NCBI Official Synonym Symbols: | SCAR3; WAVE3; Brush-1 |
NCBI Protein Information: | wiskott-Aldrich syndrome protein family member 3; protein WAVE-3; WASP family Verprolin-homologous protein 3; verprolin homology domain-containing protein 3 |
UniProt Protein Name: | Wiskott-Aldrich syndrome protein family member 3 |
UniProt Synonym Protein Names: | Protein WAVE-3; Verprolin homology domain-containing protein 3 |
Protein Family: | Wiskott-Aldrich syndrome protein family |
UniProt Gene Name: | WASF3 |
UniProt Entry Name: | WASF3_HUMAN |