VEGFB Antibody (PACO52042)
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주문- SKU:
- PACO52042
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | VEGFB Antibody (PACO52042) |
Antibody SKU: | PACO52042 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC |
Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:5000, IHC:1:20-1:200 |
Species Reactivity: | Human, Mouse, Rat |
Immunogen: | Recombinant Human Vascular endothelial growth factor B protein (22-207AA) |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
Purification Method: | >95%, Protein G purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Western Blot. Positive WB detected in: Rat heart tissue, Rat spleen tissue, Mouse heart tissue, Mouse liver tissue, Mouse kidney tissue, Mouse brain tissue. All lanes: VEGFB antibody at 3.5µg/ml. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 22 kDa. Observed band size: 28 kDa. | |
Immunohistochemistry of paraffin-embedded human endometrial cancer using PACO52042 at dilution of 1:100. | |
Immunohistochemistry of paraffin-embedded human gastric cancer using PACO52042 at dilution of 1:100. |
Background: | Growth factor for endothelial cells. VEGF-B167 binds heparin and neuropilin-1 whereas the binding to neuropilin-1 of VEGF-B186 is regulated by proteolysis. |
Synonyms: | Vascular endothelial growth factor B (VEGF-B) (VEGF-related factor) (VRF), VEGFB, VRF |
UniProt Protein Function: | VEGFB: Growth factor for endothelial cells. VEGF-B167 binds heparin and neuropilin-1 whereas the binding to neuropilin-1 of VEGF-B186 is regulated by proteolysis. Homodimer; disulfide-linked. Can also form heterodimer with VEGF. Expressed in all tissues except liver. Highest levels found in heart, skeletal muscle and pancreas. Belongs to the PDGF/VEGF growth factor family. 2 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Secreted, signal peptide; Secreted; Cell cycle regulation; Motility/polarity/chemotaxis; Cytokine Chromosomal Location of Human Ortholog: 11q13 Cellular Component: extracellular region Molecular Function:protein binding Biological Process: platelet degranulation; vascular endothelial growth factor receptor signaling pathway |
NCBI Summary: | This gene encodes a member of the PDGF (platelet-derived growth factor)/VEGF (vascular endothelial growth factor) family. The VEGF family members regulate the formation of blood vessels and are involved in endothelial cell physiology. This member is a ligand for VEGFR-1 (vascular endothelial growth factor receptor 1) and NRP-1 (neuropilin-1). Studies in mice showed that this gene was co-expressed with nuclear-encoded mitochondrial genes and the encoded protein specifically controlled endothelial uptake of fatty acids. Alternatively spliced transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Sep 2011] |
UniProt Code: | P49765 |
NCBI GenInfo Identifier: | 17380554 |
NCBI Gene ID: | 7423 |
NCBI Accession: | P49765.2 |
UniProt Secondary Accession: | P49765,Q16528, |
UniProt Related Accession: | P49765 |
Molecular Weight: | 21,261 Da |
NCBI Full Name: | Vascular endothelial growth factor B |
NCBI Synonym Full Names: | vascular endothelial growth factor B |
NCBI Official Symbol: | VEGFB |
NCBI Official Synonym Symbols: | VRF; VEGFL |
NCBI Protein Information: | vascular endothelial growth factor B |
UniProt Protein Name: | Vascular endothelial growth factor B |
UniProt Synonym Protein Names: | VEGF-related factor; VRF |
Protein Family: | Vascular endothelial growth factor |
UniProt Gene Name: | VEGFB |
UniProt Entry Name: | VEGFB_HUMAN |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |