UQCRFS1 Antibody (PACO31864)
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주문- SKU:
- PACO31864
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | UQCRFS1 Antibody (PACO31864) |
Antibody SKU: | PACO31864 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC |
Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:1000-1:5000, IHC:1:20-1:200 |
Species Reactivity: | Human |
Immunogen: | Recombinant Human Cytochrome b-c1 complex subunit Rieske, mitochondrial protein (79-274AA) |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
Purification Method: | >95%, Protein G purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
![]() | Western blot All lanes: UQCRFS1 antibody at 2µg/ml Lane 1: EC109 whole cell lysate Lane 2: 293T whole cell lysate Secondary Goat polyclonal to rabbit IgG at 1/15000 dilution Predicted band size: 30 kDa Observed band size: 30 kDa . |
![]() | Immunohistochemistry of paraffin-embedded human colon cancer using PACO31864 at dilution of 1:100. |
Background: | Cytochrome b-c1 complex subunit Rieske, mitochondrial: Component of the mitochondrial ubiquinol-cytochrome c reductase complex dimer (complex III dimer), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis. Incorporation of UQCRFS1 is the penultimate step in complex III assembly. Cytochrome b-c1 complex subunit 9: Possible component of the mitochondrial ubiquinol-cytochrome c reductase complex dimer (complex III dimer), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis. UQCRFS1 undergoes proteolytic processing once it is incorporated in the complex III dimer, including this fragment, called subunit 9, which corresponds to the transit peptide. The proteolytic processing is necessary for the correct insertion of UQCRFS1 in the complex III dimer, but the persistence of UQCRFS1-derived fragments may prevent newly imported UQCRFS1 to be processed and assembled into complex III and is detrimental for the complex III structure and function. It is therefore unsure whether the UQCRFS1 fragments, including this fragment, are structural subunits. |
Synonyms: | Cytochrome b-c1 complex subunit Rieske, mitochondrial (EC 1.10.2.2) (Complex III subunit 5) (Cytochrome b-c1 complex subunit 5) (Rieske iron-sulfur protein) (RISP) (Rieske protein UQCRFS1) (Ubiquinol-cytochrome c reductase iron-sulfur subunit) [Cleaved into: Cytochrome b-c1 complex subunit 9 (Su9) (Subunit 9) (8 kDa subunit 9) (Complex III subunit IX) (Cytochrome b-c1 complex subunit 11) (Ubiquinol-cytochrome c reductase 8 kDa protein)], UQCRFS1 |
UniProt Protein Function: | UQCRFS1: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis. |
UniProt Protein Details: | Protein type:EC 1.10.2.2; Mitochondrial; Energy Metabolism - oxidative phosphorylation; Oxidoreductase Chromosomal Location of Human Ortholog: 19q12 Cellular Component: mitochondrion; mitochondrial inner membrane; mitochondrial respiratory chain complex III Molecular Function:2 iron, 2 sulfur cluster binding; metal ion binding; ubiquinol-cytochrome-c reductase activity; protein complex binding Biological Process: response to drug; response to antibiotic; cellular metabolic process; response to hormone stimulus |
UniProt Code: | P47985 |
NCBI GenInfo Identifier: | 143811471 |
NCBI Gene ID: | 7386 |
NCBI Accession: | P47985.2 |
UniProt Secondary Accession: | P47985,Q6NVX5, Q9UPH2, A8K519, |
UniProt Related Accession: | P47985 |
Molecular Weight: | 29,668 Da |
NCBI Full Name: | Cytochrome b-c1 complex subunit Rieske, mitochondrial |
NCBI Synonym Full Names: | ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1 |
NCBI Official Symbol: | UQCRFS1 |
NCBI Official Synonym Symbols: | RIP1; RIS1; RISP; UQCR5 |
NCBI Protein Information: | cytochrome b-c1 complex subunit Rieske, mitochondrial; complex III subunit 5; Rieske iron-sulfur protein; cytochrome b-c1 complex subunit 5; ubiquinol-cytochrome c reductase iron-sulfur subunit |
UniProt Protein Name: | Cytochrome b-c1 complex subunit Rieske, mitochondrial |
UniProt Synonym Protein Names: | Complex III subunit 5; Cytochrome b-c1 complex subunit 5; Rieske iron-sulfur protein; RISP; Ubiquinol-cytochrome c reductase iron-sulfur subunitCleaved into the following chain:Cytochrome b-c1 complex subunit 11Alternative name(s):Complex III subunit IX; Ubiquinol-cytochrome c reductase 8 kDa protein |
Protein Family: | Cytochrome b-c1 complex |
UniProt Gene Name: | UQCRFS1 |
UniProt Entry Name: | UCRI_HUMAN |
Antibodies |
Anti-UQCRFS1 Antibody (CAB14069) |
Anti-UQCRFS1 Antibody (CAB6784) |
Anti-UQCRFS1 Antibody (CAB9517) |
UQCRFS1 Antibody (PACO13104) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
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Anti-HRP-conjugated Beta Actin Antibody (CABC028) |