UPK1B Antibody (PACO43893)
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주문- SKU:
- PACO43893
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | UPK1B Antibody (PACO43893) |
Antibody SKU: | PACO43893 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA |
Recommended Dilutions: | |
Species Reactivity: | Human |
Immunogen: | Recombinant Human Uroplakin-1b protein (110-230AA) |
Form: | Liquid |
Storage Buffer: | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Purification Method: | Antigen Affinity Purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Background: | Component of the asymmetric unit membrane (AUM); a highly specialized biomembrane elaborated by terminally differentiated urothelial cells. May play an important role in normal bladder epithelial physiology, possibly in regulating membrane permeability of superficial umbrella cells or in stabilizing the apical membrane through AUM/cytoskeletal interactions. |
Synonyms: | Uroplakin-1b (UP1b) (Tetraspanin-20) (Tspan-20) (Uroplakin Ib) (UPIb), UPK1B, TSPAN20 |
UniProt Protein Function: | UPK1B: Component of the asymmetric unit membrane (AUM); a highly specialized biomembrane elaborated by terminally differentiated urothelial cells. May play an important role in normal bladder epithelial physiology, possibly in regulating membrane permeability of superficial umbrella cells or in stabilizing the apical membrane through AUM/cytoskeletal interactions. Belongs to the tetraspanin (TM4SF) family. |
UniProt Protein Details: | Protein type:Membrane protein, multi-pass; Membrane protein, integral Chromosomal Location of Human Ortholog: 3q13.32 Cellular Component: integral to plasma membrane Biological Process: cell surface receptor linked signal transduction; epithelial cell differentiation |
NCBI Summary: | The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is found in the asymmetrical unit membrane (AUM) where it can form a complex with other transmembrane 4 superfamily proteins. It may play a role in normal bladder epithelial physiology, possibly in regulating membrane permeability of superficial umbrella cells or in stabilizing the apical membrane through AUM/cytoskeletal interactions. The use of alternate polyadenylation sites has been found for this gene. [provided by RefSeq, Jul 2008] |
UniProt Code: | O75841 |
NCBI GenInfo Identifier: | 313104322 |
NCBI Gene ID: | 7348 |
NCBI Accession: | O75841.5 |
UniProt Secondary Accession: | O75841,O60753, Q9UIM2, Q9UNX6, |
UniProt Related Accession: | O75841 |
Molecular Weight: | 29,643 Da |
NCBI Full Name: | Uroplakin-1b |
NCBI Synonym Full Names: | uroplakin 1B |
NCBI Official Symbol: | UPK1B |
NCBI Official Synonym Symbols: | UPIB; UPK1; TSPAN20 |
NCBI Protein Information: | uroplakin-1b |
UniProt Protein Name: | Uroplakin-1b |
UniProt Synonym Protein Names: | Tetraspanin-20; Tspan-20; Uroplakin Ib; UPIb |
Protein Family: | Uroplakin |
UniProt Gene Name: | UPK1B |
UniProt Entry Name: | UPK1B_HUMAN |