UNG Antibody (PACO21730)
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주문- SKU:
- PACO21730
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | UNG Antibody (PACO21730) |
Antibody SKU: | PACO21730 |
Size: | 100ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB |
Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:3000 |
Species Reactivity: | Human, Mouse, Rat |
Immunogen: | Synthesized peptide derived from internal of human UNG. |
Form: | Liquid |
Storage Buffer: | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
![]() | Western blot analysis of extracts from HepG2 cells and COLO cells, using UNG antibody. |
Background: | Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. HAMAP-Rule MF_03166 Haug T., FEBS Lett. 353:180-184(1994). |
Synonyms: | DGU; EC 3.2.2; UDG; UNG15; uracil-DNA glycosylase |
UniProt Protein Function: | Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. |
NCBI Summary: | This gene encodes one of several uracil-DNA glycosylases. One important function of uracil-DNA glycosylases is to prevent mutagenesis by eliminating uracil from DNA molecules by cleaving the N-glycosylic bond and initiating the base-excision repair (BER) pathway. Uracil bases occur from cytosine deamination or misincorporation of dUMP residues. Alternative promoter usage and splicing of this gene leads to two different isoforms: the mitochondrial UNG1 and the nuclear UNG2. The UNG2 term was used as a previous symbol for the CCNO gene (GeneID 10309), which has been confused with this gene, in the literature and some databases. [provided by RefSeq, Nov 2010] |
UniProt Code: | P13051 |
NCBI GenInfo Identifier: | 6224979 |
NCBI Gene ID: | 7374 |
NCBI Accession: | NP_003353.1 |
UniProt Secondary Accession: | P13051,O00637, O00719, Q93028, A8K5M6, B2R8Y1, |
UniProt Related Accession: | P13051 |
Molecular Weight: | |
NCBI Full Name: | uracil-DNA glycosylase isoform UNG1 |
NCBI Synonym Full Names: | uracil DNA glycosylase |
NCBI Official Symbol: | UNG |
NCBI Official Synonym Symbols: | DGU; UDG; UNG1; UNG2; HIGM4; HIGM5; UNG15 |
NCBI Protein Information: | uracil-DNA glycosylase |
UniProt Protein Name: | Uracil-DNA glycosylase |
Protein Family: | Probable uracil-DNA glycosylase |
UniProt Gene Name: | UNG |
Antibodies |
Anti-UNG Antibody (CAB1261) |
Anti-UNG Antibody (CAB13155) |
UNG Antibody (PACO06849) |
UNG Antibody (PACO13096) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
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Anti-HRP-conjugated Beta Actin Antibody (CABC028) |