UBE2F Antibody (PACO45537)
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주문- SKU:
- PACO45537
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | UBE2F Antibody (PACO45537) |
Antibody SKU: | PACO45537 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, IHC |
Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200 |
Species Reactivity: | Human |
Immunogen: | Recombinant Human NEDD8-conjugating enzyme UBE2F protein (1-185AA) |
Form: | Liquid |
Storage Buffer: | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Purification Method: | Antigen Affinity Purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
![]() | Immunohistochemistry of paraffin-embedded human brain tissue using PACO45537 at dilution of 1:100. |
Background: | Accepts the ubiquitin-like protein NEDD8 from the UBA3-NAE1 E1 complex and catalyzes its covalent attachment to other proteins. The specific interaction with the E3 ubiquitin ligase RBX2, but not RBX1, suggests that the RBX2-UBE2F complex neddylates specific target proteins, such as CUL5. |
Synonyms: | NEDD8-conjugating enzyme UBE2F (EC 2.3.2.-) (NEDD8 carrier protein UBE2F) (NEDD8 protein ligase UBE2F) (NEDD8-conjugating enzyme 2) (RING-type E3 NEDD8 transferase UBE2F) (Ubiquitin-conjugating enzyme E2 F), UBE2F, NCE2 |
UniProt Protein Function: | UBE2F: Accepts the ubiquitin-like protein NEDD8 from the UBA3- NAE1 E1 complex and catalyzes its covalent attachment to other proteins. The specific interaction with the E3 ubiquitin ligase RBX2, but not RBX1, suggests that the RBX2-UBE2F complex neddylates specific target proteins, such as CUL5. Belongs to the ubiquitin-conjugating enzyme family. UBE2F subfamily. 5 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:EC 6.3.2.19; Ubiquitin ligase; EC 6.3.2.-; Ligase; Ubiquitin conjugating system Chromosomal Location of Human Ortholog: 2q37.3 Cellular Component: cytoplasm Molecular Function:protein binding; ubiquitin protein ligase binding; ATP binding; NEDD8 ligase activity; ligase activity Biological Process: protein neddylation; protein ubiquitination |
UniProt Code: | Q969M7 |
NCBI GenInfo Identifier: | 74751725 |
NCBI Gene ID: | 140739 |
NCBI Accession: | Q969M7.1 |
UniProt Related Accession: | Q969M7 |
Molecular Weight: | Predicted Molecular Mass: 24.8kDaAccurate Molecular Mass: 25kDa |
NCBI Full Name: | NEDD8-conjugating enzyme UBE2F |
NCBI Synonym Full Names: | ubiquitin conjugating enzyme E2 F (putative) |
NCBI Official Symbol: | UBE2F |
NCBI Official Synonym Symbols: | NCE2 |
NCBI Protein Information: | NEDD8-conjugating enzyme UBE2F |
UniProt Protein Name: | NEDD8-conjugating enzyme UBE2F |
UniProt Synonym Protein Names: | NEDD8 carrier protein UBE2F; NEDD8 protein ligase UBE2F; NEDD8-conjugating enzyme 2; Ubiquitin-conjugating enzyme E2 F |
Protein Family: | NEDD8-conjugating enzyme |
UniProt Gene Name: | UBE2F |
UniProt Entry Name: | UBE2F_HUMAN |