TXNDC5 Antibody (PACO44561)
제품 코드를 사용하여 Assay Genie 메인 사이트를 통해 주문합니다.
주문- SKU:
- PACO44561
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | TXNDC5 Antibody (PACO44561) |
Antibody SKU: | PACO44561 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC |
Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:1000-1:5000, IHC:1:20-1:200 |
Species Reactivity: | Human, Mouse |
Immunogen: | Recombinant Human Thioredoxin domain-containing protein 5 protein (1-324AA) |
Form: | Liquid |
Storage Buffer: | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Purification Method: | Antigen Affinity Purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
![]() | Western blot. All lanes: TXNDC5 antibody at 5.75µg/ml. Lane 1: HepG2 whole cell lysate. Lane 2: Colo320 whole cell lysate. Lane 3: Mouse brain tissue. Lane 4: Mouse stomach tissue. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 48, 37 kDa. Observed band size: 48 kDa.. |
![]() | Immunohistochemistry of paraffin-embedded human gastric cancer using PACO44561 at dilution of 1:100. |
![]() | Immunohistochemistry of paraffin-embedded human colon cancer using PACO44561 at dilution of 1:100. |
Background: | Possesses thioredoxin activity. Has been shown to reduce insulin disulfide bonds. Also complements protein disulfide-isomerase deficiency in yeast (By similarity). |
Synonyms: | Thioredoxin domain-containing protein 5 (Endoplasmic reticulum resident protein 46) (ER protein 46) (ERp46) (Thioredoxin-like protein p46), TXNDC5, TLP46 |
UniProt Protein Function: | TXNDC5: Possesses thioredoxin activity. Has been shown to reduce insulin disulfide bonds. Also complements protein disulfide- isomerase deficiency in yeast. Belongs to the protein disulfide isomerase family. |
UniProt Protein Details: | Protein type:Secreted; Secreted, signal peptide Chromosomal Location of Human Ortholog: 6p24.3 Cellular Component: lysosomal lumen; endoplasmic reticulum; endoplasmic reticulum lumen Molecular Function:protein binding; protein disulfide isomerase activity Biological Process: protein folding; cell redox homeostasis; post-Golgi vesicle-mediated transport; apoptotic cell clearance; negative regulation of apoptosis |
NCBI Summary: | This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The encoded protein has an N-terminal endoplasmic reticulum (ER)-signal sequence, three catalytically active thioredoxin domains and a C-terminal ER-retention sequence. Its expression is induced by hypoxia and its role may be to protect hypoxic cells from apoptosis. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring upstream BLOC1S5 gene. [provided by RefSeq, Dec 2016] |
UniProt Code: | Q8NBS9 |
NCBI GenInfo Identifier: | 29839560 |
NCBI Gene ID: | 81567 |
NCBI Accession: | Q8NBS9.2 |
UniProt Related Accession: | Q8NBS9 |
Molecular Weight: | |
NCBI Full Name: | Thioredoxin domain-containing protein 5 |
NCBI Synonym Full Names: | thioredoxin domain containing 5 |
NCBI Official Symbol: | TXNDC5 |
NCBI Official Synonym Symbols: | HCC2; ERP46; HCC-2; STRF8; PDIA15; UNQ364; ENDOPDI |
NCBI Protein Information: | thioredoxin domain-containing protein 5 |
UniProt Protein Name: | Thioredoxin domain-containing protein 5 |
UniProt Synonym Protein Names: | Endoplasmic reticulum resident protein 46; ER protein 46; ERp46; Thioredoxin-like protein p46 |
UniProt Gene Name: | TXNDC5 |
UniProt Entry Name: | TXND5_HUMAN |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |