TRIM9 Antibody (PACO41578)
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주문- SKU:
- PACO41578
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | TRIM9 Antibody (PACO41578) |
Antibody SKU: | PACO41578 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, IHC |
Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200 |
Species Reactivity: | Human |
Immunogen: | Recombinant Human E3 ubiquitin-protein ligase TRIM9 protein (1-550AA) |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
Purification Method: | >95%, Protein G purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Immunohistochemistry of paraffin-embedded human prostate cancer using PACO41578 at dilution of 1:100. | |
Immunohistochemistry of paraffin-embedded human skin tissue using PACO41578 at dilution of 1:100. |
Background: | E3 ubiquitin-protein ligase which ubiquitinates itself in cooperation with an E2 enzyme UBE2D2/UBC4 and serves as a targeting signal for proteasomal degradation. May play a role in regulation of neuronal functions and may also participate in the formation or breakdown of abnormal inclusions in neurodegenerative disorders. May act as a regulator of synaptic vesicle exocytosis by controlling the availability of SNAP25 for the SNARE complex formation. |
Synonyms: | E3 ubiquitin-protein ligase TRIM9 (EC 2.3.2.27) (RING finger protein 91) (RING-type E3 ubiquitin transferase TRIM9) (Tripartite motif-containing protein 9), TRIM9, KIAA0282 RNF91 |
UniProt Protein Function: | TRIM9: E3 ubiquitin-protein ligase which ubiquitinates itself in cooperation with an E2 enzyme UBE2D2/UBC4 and serves as a targeting signal for proteasomal degradation. May play a role in regulation of neuronal functions and may also participate in the formation or breakdown of abnormal inclusions in neurodegenerative disorders. May act as a regulator of synaptic vesicle exocytosis by controlling the availability of SNAP25 for the SNARE complex formation. Belongs to the TRIM/RBCC family. 3 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Ubiquitin conjugating system; EC 6.3.2.- Chromosomal Location of Human Ortholog: 14q22.1 Cellular Component: synaptic vesicle; cytoskeleton; dendrite; cytoplasm; cell junction Molecular Function:SNARE binding; protein homodimerization activity; zinc ion binding; ubiquitin-protein ligase activity; ligase activity Biological Process: proteasomal ubiquitin-dependent protein catabolic process; synaptic vesicle exocytosis; negative regulation of calcium ion-dependent exocytosis; protein ubiquitination |
NCBI Summary: | The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to cytoplasmic bodies. Its function has not been identified. Alternate splicing of this gene generates two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q9C026 |
NCBI GenInfo Identifier: | 39795457 |
NCBI Gene ID: | 114088 |
NCBI Accession: | AAH63872.1 |
UniProt Secondary Accession: | Q9C026,Q92557, Q96D24, Q96NI4, Q9C025, Q9C027, D3DSB7 D3DSB8, |
UniProt Related Accession: | Q9C026 |
Molecular Weight: | |
NCBI Full Name: | Tripartite motif-containing 9 |
NCBI Synonym Full Names: | tripartite motif containing 9 |
NCBI Official Symbol: | TRIM9 |
NCBI Official Synonym Symbols: | RNF91; SPRING |
NCBI Protein Information: | E3 ubiquitin-protein ligase TRIM9; RING finger protein 91; tripartite motif-containing 9; homolog of rat RING finger Spring; tripartite motif-containing protein 9 |
UniProt Protein Name: | E3 ubiquitin-protein ligase TRIM9 |
UniProt Synonym Protein Names: | RING finger protein 91; Tripartite motif-containing protein 9 |
Protein Family: | E3 ubiquitin-protein ligase |
UniProt Gene Name: | TRIM9 |
UniProt Entry Name: | TRIM9_HUMAN |