TRIM62 Antibody (PACO20702)
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주문- SKU:
- PACO20702
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | TRIM62 Antibody (PACO20702) |
Antibody SKU: | PACO20702 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC |
Recommended Dilutions: | ELISA:1:2000-1:5000, WB:1:500-1:2000, IHC:1:25-1:100 |
Species Reactivity: | Human |
Immunogen: | Synthetic peptide of human TRIM62 |
Form: | Liquid |
Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Purification Method: | Antigen affinity purification |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
![]() | The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using PACO20702(TRIM62 Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: x200). |
![]() | Gel: 8%SDS-PAGE, Lysate: 40 µg, Lane 1-2: 231 cells, hepg2 cells, Primary antibody: PACO20702(TRIM62 Antibody) at dilution 1/400, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute. |
![]() | The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using PACO20702(TRIM62 Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: x200). |
Background: | TRIM62 (tripartite motif-containing 62) is a 475 amino acid, protein that belongs to the TRIM/RBCC (Ring finger, B box, coiled-coil) family. TRIM62 contains one B box-type zinc finger, one SPRY domain and one RING-type zinc finger; a motif that has zinc-chelating activity and is involved in mediating protein-protein and protein-DNA interactions. As a member of the TRIM/RBCC family, TRIM62 may function in transcriptional regulation, cell transformation and carcinogenesis. In addition, TRIM62 expression can affect the entry of murine leukemia virus (MLV) and human immunodeficiency virus 1 (HIV). |
Synonyms: | tripartite motif containing 62 |
UniProt Protein Function: | TRIM62: Belongs to the TRIM/RBCC family. |
UniProt Protein Details: | Protein type:Ubiquitin conjugating system Chromosomal Location of Human Ortholog: 1p35.1 Cellular Component: cytoplasm; cytosol Molecular Function:ubiquitin-protein ligase activity Biological Process: activation of NF-kappaB transcription factor; innate immune response; negative regulation of viral transcription; positive regulation of I-kappaB kinase/NF-kappaB cascade; positive regulation of transcription factor activity; regulation of virion penetration into host cell |
UniProt Code: | Q9BVG3 |
NCBI GenInfo Identifier: | 74752380 |
NCBI Gene ID: | 55223 |
NCBI Accession: | Q9BVG3.1 |
UniProt Secondary Accession: | Q9BVG3,Q9NVG0, B3KVH5, B4DTE4, D3DPR1, |
UniProt Related Accession: | Q9BVG3 |
Molecular Weight: | 40,490 Da |
NCBI Full Name: | E3 ubiquitin-protein ligase TRIM62 |
NCBI Synonym Full Names: | tripartite motif containing 62 |
NCBI Official Symbol: | TRIM62 |
NCBI Official Synonym Symbols: | DEAR1 |
NCBI Protein Information: | E3 ubiquitin-protein ligase TRIM62 |
UniProt Protein Name: | E3 ubiquitin-protein ligase TRIM62 |
UniProt Synonym Protein Names: | Tripartite motif-containing protein 62 |
Protein Family: | E3 ubiquitin-protein ligase |
UniProt Gene Name: | TRIM62 |
UniProt Entry Name: | TRI62_HUMAN |
Antibodies |
Anti-TRIM62 Antibody (CAB15855) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |