TPD52L1 Antibody (PACO20738)
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주문- SKU:
- PACO20738
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | TPD52L1 Antibody (PACO20738) |
Antibody SKU: | PACO20738 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB |
Recommended Dilutions: | ELISA:1:2000-1:5000, WB:1:500-1:2000 |
Species Reactivity: | Human |
Immunogen: | Synthetic peptide of human TPD52L1 |
Form: | Liquid |
Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Purification Method: | Antigen affinity purification |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
![]() | Gel: 12%SDS-PAGE, Lysate: 40 µg, Lane 1-5: 293T cells, 231 cells, PC3 cells, A549 cells, K562 cells, Primary antibody: PACO20738(TPD52L1 Antibody) at dilution 1/300, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 10 seconds. |
Background: | This gene encodes a member of the tumor protein D52 (TPD52) family. The encoded protein contains a coiled-coil domain and may form homo- or hetero-dimer with TPD52 family members. The protein is reported to be involved in cell proliferation and calcium signaling. It also interacts with the mitogen-activated protein kinase kinase kinase 5 (MAP3K5/ASK1) and positively regulates MAP3K5-induced apoptosis. |
Synonyms: | tumor protein D52-like 1 |
UniProt Protein Function: | TPD52L1: a member of the tumor protein D52 (TPD52) family. Contains a coiled-coil domain and may form homo- or hetero-dimer with TPD52 family members. The protein is reported to be involved in cell proliferation and calcium signaling. Interacts with the apoptosis signal-regulating kinase 1 (ASK1) and positively regulates ASK1-induced apoptosis. Multiple alternatively spliced transcript variants have been observed. |
UniProt Protein Details: | Protein type:Adaptor/scaffold Chromosomal Location of Human Ortholog: 6q22-q23 Cellular Component: perinuclear region of cytoplasm; cytoplasm Molecular Function:identical protein binding; protein binding; protein homodimerization activity; protein heterodimerization activity Biological Process: positive regulation of MAP kinase activity; positive regulation of JNK cascade; G2/M transition of mitotic cell cycle; regulation of caspase activity |
NCBI Summary: | This gene encodes a member of a family of proteins that contain coiled-coil domains and may form hetero- or homomers. The encoded protein is involved in cell proliferation and calcium signaling. It also interacts with the mitogen-activated protein kinase kinase kinase 5 (MAP3K5/ASK1) and positively regulates MAP3K5-induced apoptosis. Multiple alternatively spliced transcript variants have been observed. [provided by RefSeq, Jan 2016] |
UniProt Code: | Q16890 |
NCBI GenInfo Identifier: | 12585368 |
NCBI Gene ID: | 7164 |
NCBI Accession: | Q16890.1 |
UniProt Related Accession: | Q16890 |
Molecular Weight: | |
NCBI Full Name: | Tumor protein D53 |
NCBI Synonym Full Names: | TPD52 like 1 |
NCBI Official Symbol: | TPD52L1 |
NCBI Official Synonym Symbols: | D53 |
NCBI Protein Information: | tumor protein D53 |
UniProt Protein Name: | Tumor protein D53 |
UniProt Synonym Protein Names: | Tumor protein D52-like 1 |
UniProt Gene Name: | TPD52L1 |
UniProt Entry Name: | TPD53_HUMAN |