TNNC2 Antibody (PACO43852)
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주문- SKU:
- PACO43852
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | TNNC2 Antibody (PACO43852) |
Antibody SKU: | PACO43852 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC |
Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:2000, IHC:1:20-1:200 |
Species Reactivity: | Human, Mouse |
Immunogen: | Recombinant Human Troponin C, skeletal muscle protein (1-160AA) |
Form: | Liquid |
Storage Buffer: | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Purification Method: | Antigen Affinity Purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
![]() | Western blot. All lanes: TNNC2 antibody at 10µg/ml + Mouse skeletal muscle tissue. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 18 kDa. Observed band size: 18 kDa. |
![]() | Immunohistochemistry of paraffin-embedded human colon tissue using PACO43852 at dilution of 1:100. |
Background: | Troponin is the central regulatory protein of striated muscle contraction. Tn consists of three components: Tn-I which is the inhibitor of actomyosin ATPase, Tn-T which contains the binding site for tropomyosin and Tn-C. The binding of calcium to Tn-C abolishes the inhibitory action of Tn on actin filaments. |
Synonyms: | Troponin C, skeletal muscle, TNNC2 |
UniProt Protein Function: | TNNC2: Troponin is the central regulatory protein of striated muscle contraction. Tn consists of three components: Tn-I which is the inhibitor of actomyosin ATPase, Tn-T which contains the binding site for tropomyosin and Tn-C. The binding of calcium to Tn-C abolishes the inhibitory action of Tn on actin filaments. Belongs to the troponin C family. |
UniProt Protein Details: | Protein type:Motility/polarity/chemotaxis Chromosomal Location of Human Ortholog: 20q12-q13.11 Cellular Component: cytosol; troponin complex Molecular Function:actin binding; protein binding Biological Process: muscle filament sliding; regulation of muscle contraction; skeletal muscle contraction |
NCBI Summary: | Troponin (Tn), a key protein complex in the regulation of striated muscle contraction, is composed of 3 subunits. The Tn-I subunit inhibits actomyosin ATPase, the Tn-T subunit binds tropomyosin and Tn-C, while the Tn-C subunit binds calcium and overcomes the inhibitory action of the troponin complex on actin filaments. The protein encoded by this gene is the Tn-C subunit. [provided by RefSeq, Jul 2008] |
UniProt Code: | P02585 |
NCBI GenInfo Identifier: | 136043 |
NCBI Gene ID: | 7125 |
NCBI Accession: | P02585.2 |
UniProt Secondary Accession: | P02585,Q6FH92, |
UniProt Related Accession: | P02585 |
Molecular Weight: | 18,122 Da |
NCBI Full Name: | Troponin C, skeletal muscle |
NCBI Synonym Full Names: | troponin C2, fast skeletal type |
NCBI Official Symbol: | TNNC2 |
NCBI Protein Information: | troponin C, skeletal muscle |
UniProt Protein Name: | Troponin C, skeletal muscle |
Protein Family: | Troponin |
UniProt Gene Name: | TNNC2 |
UniProt Entry Name: | TNNC2_HUMAN |
Antibodies | ELISA Kits |
Anti-TNNC2 Antibody (CAB7740) | Human TNNC2 / Troponin C Type 2 ELISA Kit |
Human TNNC2 (Troponin C Type 2) CLIA Kit (HUES00810) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |