TMPRSS11A Antibody (PACO17282)
- SKU:
- PACO17282
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | TMPRSS11A Antibody (PACO17282) |
Antibody SKU: | PACO17282 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, IHC |
Recommended Dilutions: | ELISA:1:2000-1:5000, IHC:1:25-1:100 |
Species Reactivity: | Human |
Immunogen: | Fusion protein of human TMPRSS11A |
Form: | Liquid |
Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Purification Method: | Antigen affinity purification |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using PACO17282(TMPRSS11A Antibody) at dilution 1/30, on the right is treated with fusion protein. (Original magnification: x200). | |
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using PACO17282(TMPRSS11A Antibody) at dilution 1/30, on the right is treated with fusion protein. (Original magnification: x200). |
Background: | Probable serine protease which may play a role in cellular senescence. Overexpression inhibits cell growth and induce G1 cell cycle arrest. |
Synonyms: | transmembrane protease, serine 11A |
UniProt Protein Function: | TMPRSS11A: Probable serine protease which may play a role in cellular senescence. Overexpression inhibits cell growth and induce G1 cell cycle arrest. Belongs to the peptidase S1 family. 2 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Membrane protein, integral; EC 3.4.21.-; Protease Chromosomal Location of Human Ortholog: 4q13.2 Cellular Component: integral to plasma membrane; extracellular region Molecular Function:serine-type endopeptidase activity Biological Process: proteolysis; cell cycle |
UniProt Code: | Q6ZMR5 |
NCBI GenInfo Identifier: | 167466252 |
NCBI Gene ID: | 339967 |
NCBI Accession: | NP_001107859.1 |
UniProt Secondary Accession: | Q6ZMR5,Q2NKI9, Q6JE90, Q7RTY4, Q86TK8, J3KNQ8, |
UniProt Related Accession: | Q6ZMR5 |
Molecular Weight: | 47,254 Da |
NCBI Full Name: | transmembrane protease serine 11A isoform 2 |
NCBI Synonym Full Names: | transmembrane protease, serine 11A |
NCBI Official Symbol: | TMPRSS11A |
NCBI Official Synonym Symbols: | ECRG1 |
NCBI Protein Information: | transmembrane protease serine 11A |
UniProt Protein Name: | Transmembrane protease serine 11A |
UniProt Synonym Protein Names: | Airway trypsin-like protease 1; Epidermal type-II transmembrane serine protease; Esophageal cancer-susceptibility gene 1 protein |
UniProt Gene Name: | TMPRSS11A |
UniProt Entry Name: | TM11A_HUMAN |