TMF1 Antibody (PACO59924)
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주문- SKU:
- PACO59924
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | TMF1 Antibody (PACO59924) |
Antibody SKU: | PACO59924 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC |
Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:5000, IHC:1:200-1:500 |
Species Reactivity: | Human |
Immunogen: | Recombinant Human TATA element modulatory factor protein (878-986AA) |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
Purification Method: | >95%, Protein G purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Western Blot. Positive WB detected in: Hela whole cell lysate, HepG2 whole cell lysate. All lanes: TMF1 antibody at 3.7µg/ml. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 123, 124 kDa. Observed band size: 123, 124 kDa. | |
IHC image of PACO59924 diluted at 1:300 and staining in paraffin-embedded human small intestine tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system. |
Background: | Potential coactivator of the androgen receptor. Mediates STAT3 degradation. May play critical roles in two RAB6-dependent retrograde transport processes: one from endosomes to the Golgi and the other from the Golgi to the ER. This protein binds the HIV-1 TATA element and inhibits transcriptional activation by the TATA-binding protein (TBP). |
Synonyms: | TATA element modulatory factor (TMF) (Androgen receptor coactivator 160 kDa protein) (Androgen receptor-associated protein of 160 kDa), TMF1, ARA160 |
UniProt Protein Function: | TMF1: Potential coactivator of the androgen receptor. Mediates STAT3 degradation. May play critical roles in two RAB6-dependent retrograde transport processes: one from endosomes to the Golgi and the other from the Golgi to the ER. This protein binds the HIV-1 TATA element and inhibits transcriptional activation by the TATA-binding protein (TBP). 2 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Transcription factor; Nuclear receptor co-regulator Chromosomal Location of Human Ortholog: 3p14.1 Cellular Component: Golgi membrane; Golgi apparatus; endoplasmic reticulum; nucleus Molecular Function:protein binding; DNA binding; transcription cofactor activity Biological Process: acrosome formation; transcription from RNA polymerase II promoter; positive regulation of cytokine production; luteinizing hormone secretion; sperm motility; Leydig cell differentiation; regulation of transcription, DNA-dependent; defense response to bacterium; spermatid nuclear differentiation; negative regulation of apoptosis |
UniProt Code: | P82094 |
NCBI GenInfo Identifier: | 218511858 |
NCBI Gene ID: | 7110 |
NCBI Accession: | P82094.2 |
UniProt Related Accession: | P82094 |
Molecular Weight: | |
NCBI Full Name: | TATA element modulatory factor |
NCBI Synonym Full Names: | TATA element modulatory factor 1 |
NCBI Official Symbol: | TMF1 |
NCBI Official Synonym Symbols: | TMF; ARA160 |
NCBI Protein Information: | TATA element modulatory factor |
UniProt Protein Name: | TATA element modulatory factor |
UniProt Synonym Protein Names: | Androgen receptor coactivator 160 kDa protein; Androgen receptor-associated protein of 160 kDa |
Protein Family: | TATA element modulatory factor |
UniProt Gene Name: | TMF1 |
UniProt Entry Name: | TMF1_HUMAN |
Antibodies |
Anti-TMF1 Antibody (CAB17542) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
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Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |