TMED1 Antibody (PACO45274)
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주문- SKU:
- PACO45274
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | TMED1 Antibody (PACO45274) |
Antibody SKU: | PACO45274 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, IHC |
Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200 |
Species Reactivity: | Human |
Immunogen: | Recombinant Human Transmembrane emp24 domain-containing protein 1 protein (24-194AA) |
Form: | Liquid |
Storage Buffer: | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Purification Method: | Antigen Affinity Purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Immunohistochemistry of paraffin-embedded human adrenal gland tissue using PACO45274 at dilution of 1:100. | |
Immunohistochemistry of paraffin-embedded human pancreatic tissue using PACO45274 at dilution of 1:100. |
Background: | Potential role in vesicular protein trafficking, mainly in the early secretory pathway. May act as a cargo receptor at the lumenal side for incorporation of secretory cargo molecules into transport vesicles and may be involved in vesicle coat formation at the cytoplasmic side. |
Synonyms: | Transmembrane emp24 domain-containing protein 1 (Interleukin-1 receptor-like 1 ligand) (Putative T1/ST2 receptor-binding protein) (p24 family protein gamma-1) (Tp24) (p24gamma1), TMED1, IL1RL1L IL1RL1LG |
UniProt Protein Function: | TMED1: Potential role in vesicular protein trafficking, mainly in the early secretory pathway. May act as a cargo receptor at the lumenal side for incorporation of secretory cargo molecules into transport vesicles and may be involved in vesicle coat formation at the cytoplasmic side. Belongs to the EMP24/GP25L family. |
UniProt Protein Details: | Protein type:Membrane protein, integral Chromosomal Location of Human Ortholog: 19p13.2 Cellular Component: endoplasmic reticulum; ER-Golgi intermediate compartment; Golgi apparatus Molecular Function:protein binding; receptor binding Biological Process: cell-cell signaling; signal transduction |
NCBI Summary: | This gene belongs to the TMED (transmembrane emp24 domain-containing) protein family, which is involved in the vesicular trafficking of proteins. The protein encoded by this gene was identified by its interaction with interleukin 1 receptor-like 1 (IL1RL1) and may play a role in innate immunity. This protein lacks any similarity to other interleukin 1 ligands. Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, Jul 2013] |
UniProt Code: | Q13445 |
NCBI GenInfo Identifier: | 74739789 |
NCBI Gene ID: | 11018 |
NCBI Accession: | Q13445.1 |
UniProt Related Accession: | Q13445 |
Molecular Weight: | 25,206 Da |
NCBI Full Name: | Transmembrane emp24 domain-containing protein 1 |
NCBI Synonym Full Names: | transmembrane p24 trafficking protein 1 |
NCBI Official Symbol: | TMED1 |
NCBI Official Synonym Symbols: | Tp24; p24g1; Il1rl1l; IL1RL1LG |
NCBI Protein Information: | transmembrane emp24 domain-containing protein 1 |
UniProt Protein Name: | Transmembrane emp24 domain-containing protein 1 |
UniProt Synonym Protein Names: | Interleukin-1 receptor-like 1 ligand; Putative T1/ST2 receptor-binding protein; p24 family protein gamma-1; Tp24; p24gamma1 |
Protein Family: | Transmembrane emp24 domain-containing protein |
UniProt Gene Name: | TMED1 |
UniProt Entry Name: | TMED1_HUMAN |
Antibodies |
Anti-TMED1 Antibody (CAB9963) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
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