TDRD3 Antibody (PACO47034)
제품 코드를 사용하여 Assay Genie 메인 사이트를 통해 주문합니다.
주문- SKU:
- PACO47034
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | TDRD3 Antibody (PACO47034) |
Antibody SKU: | PACO47034 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC |
Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:2000-1:5000, IHC:1:20-1:200 |
Species Reactivity: | Human |
Immunogen: | Recombinant Human Tudor domain-containing protein 3 protein (401-651AA) |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
Purification Method: | >95%, Protein G purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Western Blot. Positive WB detected in: HEK293 whole cell lysate. All lanes: TDRD3 antibody at 3µg/ml. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 74, 84 kDa. Observed band size: 74 kDa.. | |
Immunohistochemistry of paraffin-embedded human lung cancer using PACO47034 at dilution of 1:100. | |
Immunohistochemistry of paraffin-embedded human pancreatic cancer using PACO47034 at dilution of 1:100. |
Background: | Scaffolding protein that specifically recognizes and binds dimethylarginine-containing proteins. In nucleus, acts as a coactivator: recognizes and binds asymmetric dimethylation on the core histone tails associated with transcriptional activation (H3R17me2a and H4R3me2a) and recruits proteins at these arginine-methylated loci. In cytoplasm, may play a role in the assembly and/or disassembly of mRNA stress granules and in the regulation of translation of target mRNAs by binding Arg/Gly-rich motifs (GAR) in dimethylarginine-containing proteins. |
Synonyms: | Tudor domain-containing protein 3, TDRD3 |
UniProt Protein Function: | TDRD3: the Tudor domain of TDRD3 has been shown to interact with arginine-glycine-rich motifs in a methylarginine-dependent manner, and target methylated arginines physiologically. |
UniProt Protein Details: | Protein type:Histone-binding; Transcription, coactivator/corepressor; Translation; RNA-binding Chromosomal Location of Human Ortholog: 13q21.2 Cellular Component: cytoplasm; nucleus Molecular Function:transcription coactivator activity; chromatin binding; methylated histone residue binding Biological Process: chromatin modification |
UniProt Code: | Q9H7E2 |
NCBI GenInfo Identifier: | 29337133 |
NCBI Gene ID: | 81550 |
NCBI Accession: | Q9H7E2.1 |
UniProt Secondary Accession: | Q9H7E2,Q53XA6, Q6P992, B2MWP9, |
UniProt Related Accession: | Q9H7E2 |
Molecular Weight: | Calculated: 73 kDa/83 kDaObserved: 73 kDa |
NCBI Full Name: | Tudor domain-containing protein 3 |
NCBI Synonym Full Names: | tudor domain containing 3 |
NCBI Official Symbol: | TDRD3 |
NCBI Protein Information: | tudor domain-containing protein 3 |
UniProt Protein Name: | Tudor domain-containing protein 3 |
Protein Family: | Tudor domain-containing protein |
UniProt Gene Name: | TDRD3 |
UniProt Entry Name: | TDRD3_HUMAN |