TBX4 Antibody (PACO59900)
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주문- SKU:
- PACO59900
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | TBX4 Antibody (PACO59900) |
Antibody SKU: | PACO59900 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB |
Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:5000 |
Species Reactivity: | Human |
Immunogen: | Recombinant Human T-box transcription factor TBX4 protein (355-511AA) |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
Purification Method: | >95%, Protein G purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
![]() | Western Blot. Positive WB detected in: A549 whole cell lysate, HepG2 whole cell lysate. All lanes: TBX4 antibody at 4.3µg/ml. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 61 kDa. Observed band size: 61 kDa. |
Background: | Involved in the transcriptional regulation of genes required for mesoderm differentiation. Probably plays a role in limb pattern formation. |
Synonyms: | T-box transcription factor TBX4 (T-box protein 4), TBX4 |
UniProt Protein Function: | TBX4: Involved in the transcriptional regulation of genes required for mesoderm differentiation. Probably plays a role in limb pattern formation. Defects in TBX4 are the cause of small patella syndrome (SPS); also known as ischiopatellar dysplasia or Scott-Taor syndrome. SPS is an autosomal dominant skeletal dysplasia characterized by patellar aplasia or hypoplasia and by anomalies of the pelvis and feet, including disrupted ossification of the ischia and inferior pubic rami. |
UniProt Protein Details: | Protein type:DNA-binding Chromosomal Location of Human Ortholog: 17q21-q22 Molecular Function:transcription factor activity Biological Process: limb morphogenesis; skeletal morphogenesis Disease: Small Patella Syndrome |
NCBI Summary: | This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene is the human homolog of mouse Tbx4, which is closely linked to Tbx2 on mouse chromosome 11. Similarly this gene, like TBX2, maps to human chromosome 17. Expression studies in mouse and chicken show that Tbx4 is expressed in developing hindlimb, but not in forelimb buds, suggesting a role for this gene in regulating limb development and specification of limb identity. [provided by RefSeq, Jul 2008] |
UniProt Code: | P57082 |
NCBI GenInfo Identifier: | 51338786 |
NCBI Gene ID: | 9496 |
NCBI Accession: | P57082.2 |
UniProt Secondary Accession: | P57082,A5PKU7, B2RMT1, B7ZLV3, |
UniProt Related Accession: | P57082 |
Molecular Weight: | 60,275 Da |
NCBI Full Name: | T-box transcription factor TBX4 |
NCBI Synonym Full Names: | T-box 4 |
NCBI Official Symbol: | TBX4 |
NCBI Official Synonym Symbols: | SPS; ICPPS |
NCBI Protein Information: | T-box transcription factor TBX4 |
UniProt Protein Name: | T-box transcription factor TBX4 |
Protein Family: | T-box transcription factor |
UniProt Gene Name: | TBX4 |
UniProt Entry Name: | TBX4_HUMAN |
Antibodies |
Anti-TBX4 Antibody (CAB10691) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |