TBCC Antibody (PACO30286)
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주문- SKU:
- PACO30286
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | TBCC Antibody (PACO30286) |
Antibody SKU: | PACO30286 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC |
Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:5000, IHC:1:20-1:200 |
Species Reactivity: | Human |
Immunogen: | Recombinant Human Tubulin-specific chaperone C protein (2-346AA) |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
Purification Method: | >95%, Protein G purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
![]() | Western blot All lanes: TBCC antibody at 2µg/ml Lane 1: Hela whole cell lysate Lane 2: HepG2 whole cell lysate Lane 3: A549 whole cell lysate Lane 4: MCF-7 whole cell lysate Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 40 kDa Observed band size: 40 kDa . |
![]() | Immunohistochemistry of paraffin-embedded human pancreatic cancer using PACO30286 at dilution of 1:100. |
![]() | Immunohistochemistry of paraffin-embedded human colon cancer using PACO30286 at dilution of 1:100. |
Background: | Tubulin-folding protein; involved in the final step of the tubulin folding pathway. |
Synonyms: | Tubulin-specific chaperone C (Tubulin-folding cofactor C) (CFC), TBCC |
UniProt Protein Function: | TBCC: Tubulin-folding protein; involved in the final step of the tubulin folding pathway. Belongs to the TBCC family. |
UniProt Protein Details: | Chromosomal Location of Human Ortholog: 6p21.1 Cellular Component: cytoplasm; cytoskeleton; microtubule; photoreceptor connecting cilium Molecular Function:chaperone binding; GTPase activity Biological Process: post-chaperonin tubulin folding pathway; protein folding; tubulin folding |
NCBI Summary: | Cofactor C is one of four proteins (cofactors A, D, E, and C) involved in the pathway leading to correctly folded beta-tubulin from folding intermediates. Cofactors A and D are believed to play a role in capturing and stabilizing beta-tubulin intermediates in a quasi-native confirmation. Cofactor E binds to the cofactor D/beta-tubulin complex; interaction with cofactor C then causes the release of beta-tubulin polypeptides that are committed to the native state. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q15814 |
NCBI GenInfo Identifier: | 313104020 |
NCBI Gene ID: | 6903 |
NCBI Accession: | Q15814.2 |
UniProt Secondary Accession: | Q15814,Q53Y43, Q5T787, |
UniProt Related Accession: | Q15814 |
Molecular Weight: | 39,248 Da |
NCBI Full Name: | Tubulin-specific chaperone C |
NCBI Synonym Full Names: | tubulin folding cofactor C |
NCBI Official Symbol: | TBCC |
NCBI Official Synonym Symbols: | CFC |
NCBI Protein Information: | tubulin-specific chaperone C |
UniProt Protein Name: | Tubulin-specific chaperone C |
UniProt Synonym Protein Names: | Tubulin-folding cofactor C; CFC |
Protein Family: | TBCC domain-containing protein |
UniProt Gene Name: | TBCC |
UniProt Entry Name: | TBCC_HUMAN |