TAS1R3 Antibody (PACO45482)
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주문- SKU:
- PACO45482
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | TAS1R3 Antibody (PACO45482) |
Antibody SKU: | PACO45482 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC |
Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:1000-1:5000, IHC:1:20-1:200 |
Species Reactivity: | Human |
Immunogen: | Recombinant Human Taste receptor type 1 member 3 protein (400-570AA) |
Form: | Liquid |
Storage Buffer: | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Purification Method: | Antigen Affinity Purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
![]() | Western blot. All lanes: TAS1R3 antibody at 1.48µg/ml. Lane 1: K562 whole cell lysate. Lane 2: HL60 whole cell lysate. Lane 3: Hela whole cell lysate. Lane 4: HepG2 whole cell lysate. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 94 kDa. Observed band size: 94 kDa.. |
![]() | Immunohistochemistry of paraffin-embedded human pancreatic cancer using PACO45482 at dilution of 1:100. |
Background: | Putative taste receptor. TAS1R1/TAS1R3 responds to the umami taste stimulus (the taste of monosodium glutamate). TAS1R2/TAS1R3 recognizes diverse natural and synthetic sweeteners. TAS1R3 is essential for the recognition and response to the disaccharide trehalose (By similarity). Sequence differences within and between species can significantly influence the selectivity and specificity of taste responses. |
Synonyms: | Taste receptor type 1 member 3 (Sweet taste receptor T1R3), TAS1R3, T1R3 TR3 |
UniProt Protein Function: | TAS1R3: Putative taste receptor. TAS1R1/TAS1R3 responds to the umami taste stimulus (the taste of monosodium glutamate). TAS1R2/TAS1R3 recognizes diverse natural and synthetic sweeteners. TAS1R3 is essential for the recognition and response to the disaccharide trehalose. Sequence differences within and between species can significantly influence the selectivity and specificity of taste responses. Belongs to the G-protein coupled receptor 3 family. TAS1R subfamily. |
UniProt Protein Details: | Protein type:Membrane protein, multi-pass; GPCR, family 3; Membrane protein, integral; Receptor, GPCR Chromosomal Location of Human Ortholog: 1p36.33 Cellular Component: integral to membrane; plasma membrane Molecular Function:sweet taste receptor activity; taste receptor activity Biological Process: detection of chemical stimulus involved in sensory perception of sweet taste; G-protein coupled receptor protein signaling pathway; sensory perception of sweet taste; sensory perception of umami taste |
NCBI Summary: | The protein encoded by this gene is a G-protein coupled receptor involved in taste responses. The encoded protein can form a heterodimeric receptor with TAS1R1 to elicit the umami taste response, or it can bind with TAS1R2 to form a receptor for the sweet taste response. [provided by RefSeq, Nov 2015] |
UniProt Code: | Q7RTX0 |
NCBI GenInfo Identifier: | 62299063 |
NCBI Gene ID: | 83756 |
NCBI Accession: | Q7RTX0.2 |
UniProt Secondary Accession: | Q7RTX0,Q5TA49, Q8NGW9, |
UniProt Related Accession: | Q7RTX0 |
Molecular Weight: | 93,386 Da |
NCBI Full Name: | Taste receptor type 1 member 3 |
NCBI Synonym Full Names: | taste 1 receptor member 3 |
NCBI Official Symbol: | TAS1R3 |
NCBI Official Synonym Symbols: | T1R3 |
NCBI Protein Information: | taste receptor type 1 member 3 |
UniProt Protein Name: | Taste receptor type 1 member 3 |
UniProt Synonym Protein Names: | Sweet taste receptor T1R3 |
Protein Family: | Taste receptor |
UniProt Gene Name: | TAS1R3 |
UniProt Entry Name: | TS1R3_HUMAN |