TACR2 Antibody (PACO18759)
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주문- SKU:
- PACO18759
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | TACR2 Antibody (PACO18759) |
Antibody SKU: | PACO18759 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC |
Recommended Dilutions: | ELISA:1:2000-1:5000, WB:1:500-1:2000, IHC:1:25-1:100 |
Species Reactivity: | Human |
Immunogen: | Synthetic peptide of human TACR2 |
Form: | Liquid |
Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Purification Method: | Antigen affinity purification |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
![]() | The image on the left is immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using PACO18759(TACR2 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: x200). |
![]() | Gel: 12%SDS-PAGE, Lysate: 30 μg, Lane 1-2: K562 cells, hela cells, Primary antibody: PACO18759(TACR2 Antibody) at dilution 1/400, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 30 seconds. |
![]() | The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using PACO18759(TACR2 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: x200). |
Background: | This gene belongs to a family of genes that function as receptors for tachykinins. Receptor affinities are specified by variations in the 5'-end of the sequence. The receptors belonging to this family are characterized by interactions with G proteins and 7 hydrophobic transmembrane regions. This gene encodes the receptor for the tachykinin neuropeptide substance K, also referred to as neurokinin A. |
Synonyms: | tachykinin receptor 2 |
UniProt Protein Function: | TACR2: This is a receptor for the tachykinin neuropeptide substance K (neurokinin A). It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinity of this receptor to tachykinins is: substance K > neuromedin-K > substance P. Belongs to the G-protein coupled receptor 1 family. |
UniProt Protein Details: | Protein type:GPCR, family 1; Receptor, GPCR; Membrane protein, integral; Membrane protein, multi-pass; Motility/polarity/chemotaxis Chromosomal Location of Human Ortholog: 10q22.1 Cellular Component: integral to plasma membrane; plasma membrane Molecular Function:substance K receptor activity; protein binding; tachykinin receptor activity Biological Process: negative regulation of luteinizing hormone secretion; tachykinin signaling pathway; muscle contraction; intestine smooth muscle contraction; operant conditioning; response to electrical stimulus; excretion; positive regulation of vascular permeability; positive regulation of acetylcholine secretion |
NCBI Summary: | This gene belongs to a family of genes that function as receptors for tachykinins. Receptor affinities are specified by variations in the 5'-end of the sequence. The receptors belonging to this family are characterized by interactions with G proteins and 7 hydrophobic transmembrane regions. This gene encodes the receptor for the tachykinin neuropeptide substance K, also referred to as neurokinin A. [provided by RefSeq, Jul 2008] |
UniProt Code: | P21452 |
NCBI GenInfo Identifier: | 229462950 |
NCBI Gene ID: | 6865 |
NCBI Accession: | P21452.3 |
UniProt Secondary Accession: | P21452,Q4QRI5, Q8NGQ8, Q9UDE6, Q9UDE7, A8K7I1, |
UniProt Related Accession: | P21452 |
Molecular Weight: | 398 |
NCBI Full Name: | Substance-K receptor |
NCBI Synonym Full Names: | tachykinin receptor 2 |
NCBI Official Symbol: | TACR2 |
NCBI Official Synonym Symbols: | SKR; NK2R; NKNAR; TAC2R |
NCBI Protein Information: | substance-K receptor; NK-2R; NK-2 receptor; substance K receptor; neurokinin 2 receptor; neurokinin A receptor; seven transmembrane helix receptor |
UniProt Protein Name: | Substance-K receptor |
UniProt Synonym Protein Names: | NK-2 receptor; NK-2R; Neurokinin A receptor; Tachykinin receptor 2 |
Protein Family: | Substance-K receptor |
UniProt Gene Name: | TACR2 |
UniProt Entry Name: | NK2R_HUMAN |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
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Anti-HRP-conjugated Beta Actin Antibody (CABC028) |