SYT7 Antibody (PACO15050)
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주문- SKU:
- PACO15050
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | SYT7 Antibody (PACO15050) |
Antibody SKU: | PACO15050 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC |
Recommended Dilutions: | ELISA:1:1000-1:5000, WB:1:500-1:2000, IHC:1:15-1:50 |
Species Reactivity: | Human, Mouse |
Immunogen: | Fusion protein of human SYT7 |
Form: | Liquid |
Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Purification Method: | Antigen affinity purification |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
The image on the left is immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using PACO15050(SYT7 Antibody) at dilution 1/15, on the right is treated with fusion protein. (Original magnification: x200). | |
Gel: 10%SDS-PAGE, Lysate: 40 μg, Lane 1-2: Lncap cells, SKOV3 cells, Primary antibody: PACO15050(SYT7 Antibody) at dilution 1/200, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute. | |
The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using PACO15050(SYT7 Antibody) at dilution 1/15, on the right is treated with fusion protein. (Original magnification: x200). |
Background: | This gene is a member of the synaptotagmin gene family and encodes a protein similar to other family members that mediate calcium-dependent regulation of membrane trafficking in synaptic transmission. A similar protein in rodents mediates hormone secretion and lysosome exocytosis. In humans, expression of this gene has been associated with prostate cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. |
Synonyms: | synaptotagmin VII |
UniProt Protein Function: | SYT7: May be involved in Ca(2+)-dependent exocytosis of secretory vesicles through Ca(2+) and phospholipid binding to the C2 domain or may serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis. Belongs to the synaptotagmin family. |
UniProt Protein Details: | Protein type:Membrane protein, integral Chromosomal Location of Human Ortholog: 11q12.2 Cellular Component: lysosome; peroxisome; plasma membrane; synaptic vesicle Molecular Function:calcium ion binding; calcium-dependent phospholipid binding; calmodulin binding; clathrin binding; phosphatidylinositol-4,5-bisphosphate binding; protein binding; syntaxin binding Biological Process: calcium ion-dependent exocytosis of neurotransmitter; phagocytosis; plasma membrane repair; regulation of bone remodeling; regulation of calcium ion-dependent exocytosis; regulation of insulin secretion; regulation of phagocytosis; vesicle fusion |
NCBI Summary: | This gene is a member of the synaptotagmin gene family and encodes a protein similar to other family members that mediate calcium-dependent regulation of membrane trafficking in synaptic transmission. A similar protein in rodents mediates hormone secretion and lysosome exocytosis. In humans, expression of this gene has been associated with prostate cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Oct 2011] |
UniProt Code: | O43581 |
NCBI GenInfo Identifier: | 206729907 |
NCBI Gene ID: | 9066 |
NCBI Accession: | O43581.3 |
UniProt Secondary Accession: | O43581,Q08AH6, F5GZC2, F5GZU9, F5H126, F5H1N2, F5H6C1 |
UniProt Related Accession: | O43581 |
Molecular Weight: | 46kDa |
NCBI Full Name: | Synaptotagmin-7 |
NCBI Synonym Full Names: | synaptotagmin 7 |
NCBI Official Symbol: | SYT7 |
NCBI Official Synonym Symbols: | IPCA7; IPCA-7; SYTVII; PCANAP7; SYT-VII |
NCBI Protein Information: | synaptotagmin-7 |
UniProt Protein Name: | Synaptotagmin-7 |
UniProt Synonym Protein Names: | IPCA-7; Prostate cancer-associated protein 7; Synaptotagmin VII; SytVII |
Protein Family: | Synaptotagmin |
UniProt Gene Name: | SYT7 |
Antibodies |
Anti-SYT7 Antibody (CAB12757) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |