SYNE3 Antibody (PACO02559)
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주문- SKU:
- PACO02559
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IF
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | SYNE3 Antibody |
Antibody SKU: | PACO02559 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IF |
Recommended Dilutions: | WB:1:500-1:2000, IF:1:200-1:1000 |
Species Reactivity: | Human, Mouse |
Immunogen: | synthesized peptide derived from the Internal region of human Nesprin-3. |
Form: | Liquid |
Storage Buffer: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Synonyms: | SYNE3; C14orf49; Nesprin-3; Nuclear envelope spectrin repeat protein 3 |
UniProt Protein Function: | SYNE3: Component of SUN-protein-containing multivariate complexes also called LINC complexes which link the nucleoskeleton and cytoskeleton by providing versatile outer nuclear membrane attachment sites for cytoskeletal filaments. Involved in the maintenance of nuclear organization and structural integrity. Probable anchoring protein which tethers the nucleus to the cytoskeleton by binding PLEC which can associate with the intermediate filament system. Plays a role in the regulation of aortic epithelial cell morphology, and is required for flow- induced centrosome polarization and directional migration in aortic endothelial cells. Belongs to the nesprin family. 3 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Membrane protein, integral Chromosomal Location of Human Ortholog: 14q32.13 Cellular Component: membrane; nuclear envelope Molecular Function:actin filament binding; protein binding Biological Process: cytoskeleton organization and biogenesis; regulation of cell shape |
UniProt Code: | Q6ZMZ3 |
NCBI GenInfo Identifier: | 134035037 |
NCBI Gene ID: | 161176 |
NCBI Accession: | Q6ZMZ3.2 |
UniProt Secondary Accession: | Q6ZMZ3,Q86SX5, Q8N7G8, A6H8H3, |
UniProt Related Accession: | Q6ZMZ3 |
Molecular Weight: | 68,582 Da |
NCBI Full Name: | Nesprin-3 |
NCBI Synonym Full Names: | spectrin repeat containing nuclear envelope family member 3 |
NCBI Official Symbol: | SYNE3 |
NCBI Official Synonym Symbols: | NET53; Nesp3; C14orf49 |
NCBI Protein Information: | nesprin-3 |
UniProt Protein Name: | Nesprin-3 |
UniProt Synonym Protein Names: | Nuclear envelope spectrin repeat protein 3 |
Protein Family: | Nesprin |
UniProt Gene Name: | SYNE3 |
UniProt Entry Name: | SYNE3_HUMAN |