SUN1 Antibody (PACO62011)
- SKU:
- PACO62011
- Product type:
- Antibody
- Reactivity:
- Arabidopsis thaliana
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
| Antibody Name: | SUN1 Antibody (PACO62011) |
| Antibody SKU: | PACO62011 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:2000 |
| Species Reactivity: | Arabidopsis thaliana |
| Immunogen: | Recombinant Arabidopsis thaliana SUN domain-containing protein 1 protein (2-105AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western Blot. Positive WB detected in: Spinacia oleracea leaf tissue. All lanes: SUN1 antibody at 1:1000. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 52 kDa. Observed band size: 52 kDa. |
| Background: | Component of SUN-protein-containing multivariate complexes also called LINC complexes which link the nucleoskeleton and cytoskeleton by providing versatile outer nuclear membrane attachment sites for cytoskeletal filaments. Required for the maintenance and/or formation of polarized nuclear shape in root hairs. Modulates the anchoring and mobility of WIP proteins and RANGAP1 in the nuclear envelope (NE). In association with SUN2, may be involved in telomere attachment to nuclear envelope in the prophase of meiosis. As component of the SUN-WIP-WIT2-KAKU1 complex, mediates the transfer of cytoplasmic forces to the nuclear envelope (NE), leading to nuclear shape changes. |
| Synonyms: | SUN domain-containing protein 1 (AtSUN1), SUN1 |
| UniProt Protein Function: | Component of SUN-protein-containing multivariate complexes also called LINC complexes which link the nucleoskeleton and cytoskeleton by providing versatile outer nuclear membrane attachment sites for cytoskeletal filaments (PubMed:24667841, PubMed:25759303). Required for the maintenance and/or formation of polarized nuclear shape in root hairs (PubMed:21294795, PubMed:25759303). Modulates the anchoring and mobility of WIP proteins and RANGAP1 in the nuclear envelope (NE) (PubMed:22270916). In association with SUN2, may be involved in telomere attachment to nuclear envelope in the prophase of meiosis (PubMed:25412930). As component of the SUN-WIP-WIT2-KAKU1 complex, mediates the transfer of cytoplasmic forces to the nuclear envelope (NE), leading to nuclear shape changes (PubMed:25759303). |
| UniProt Protein Details: | |
| NCBI Summary: | Encodes a member of the Sad1/UNC-84 (SUN)-domain proteins: AtSUN1(At5g04990), AtSUN2(AT3G10730). SUN domain proteins are part of the cytoskeletal-nucleoskeletal bridging complexes. AtSUN1 and AtSUN2 are localized to the nuclear envelope and are present as homomers and heteromers in vivo.Encodes an outer nuclear membrane protein that anchors RanGAP1 to the nuclear envelope. It interacts with WPP domain interacting-proteins (WIPs). It is involved in maintaining the elongated nuclear shape of epidermal cells. |
| UniProt Code: | Q9FF75 |
| NCBI GenInfo Identifier: | 15238380 |
| NCBI Gene ID: | 830381 |
| NCBI Accession: | NP_196118.1 |
| UniProt Secondary Accession: | Q9FF75 |
| UniProt Related Accession: | Q9FF75 |
| Molecular Weight: | 51,502 Da |
| NCBI Full Name: | SAD1/UNC-84 domain protein 1 |
| NCBI Synonym Full Names: | |
| NCBI Official Symbol: | SUN1 |
| NCBI Official Synonym Symbols: | ARABIDOPSIS SAD1/UNC-84 DOMAIN PROTEIN 1; ATSUN1; MUG13.15; MUG13_15; SAD1/UNC-84 domain protein 1 |
| NCBI Protein Information: | SAD1/UNC-84 domain protein 1 |
| UniProt Protein Name: | SUN domain-containing protein 1 |
| UniProt Synonym Protein Names: | |
| Protein Family: | Secreted beta-glucosidase |
| UniProt Gene Name: | SUN1 |
| UniProt Entry Name: |
Related Products
Anti-SUN1 Antibody (CAB16024)
Human TP53 antibody(p53 antibody) ELISA Kit
Human CLUSTERIN ANTIBODY (CLUSTERIN ANTIBODY) ELISA Kit (HUFI04703)
