SULT1A3 Antibody (PACO43619)
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주문- SKU:
- PACO43619
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | SULT1A3 Antibody (PACO43619) |
Antibody SKU: | PACO43619 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC |
Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:2000, IHC:1:20-1:200 |
Species Reactivity: | Human, Mouse |
Immunogen: | Recombinant Human Sulfotransferase 1A3 protein (1-295AA) |
Form: | Liquid |
Storage Buffer: | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Purification Method: | Antigen Affinity Purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
![]() | Western blot. All lanes: Sulfotransferase 1A3 antibody at 10µg/ml. Lane 1: A549 whole cell lysate. Lane 2: Mouse liver tissue. Lane 2: Mouse kidney tissue. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 35, 23 kDa. Observed band size: 35 kDa. |
![]() | Immunohistochemistry of paraffin-embedded human placenta tissue using PACO43619 at dilution of 1:100. |
![]() | Immunohistochemistry of paraffin-embedded human lung tissue using PACO43619 at dilution of 1:100. |
Background: | Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of phenolic monoamines (neurotransmitters such as dopamine, norepinephrine and serotonin) and phenolic and catechol drugs. |
Synonyms: | Sulfotransferase 1A3 (ST1A3) (EC 2.8.2.1) (Aryl sulfotransferase 1A3/1A4) (Catecholamine-sulfating phenol sulfotransferase) (HAST3) (M-PST) (Monoamine-sulfating phenol sulfotransferase) (Placental estrogen sulfotransferase) (Sulfotransferase 1A3/1A4) (Sulfotransferase, monoamine-preferring) (Thermolabile phenol sulfotransferase) (TL-PST), SULT1A3, STM |
UniProt Protein Function: | SULT1A3: Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of phenolic monoamines (neurotransmitters such as dopamine, norepinephrine and serotonin) and phenolic and catechol drugs. Belongs to the sulfotransferase 1 family. 2 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:EC 2.8.2.1; Energy Metabolism - sulfur; Transferase Chromosomal Location of Human Ortholog: 16p11.2 Cellular Component: cytosol Molecular Function:amine sulfotransferase activity; aryl sulfotransferase activity; protein binding; sulfate binding; sulfotransferase activity Biological Process: 3'-phosphoadenosine 5'-phosphosulfate metabolic process; dopamine catabolic process; dopamine receptor signaling pathway; ethanol catabolic process; flavonoid metabolic process; sulfation; xenobiotic metabolic process |
NCBI Summary: | Sulfotransferase enzymes catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs, and xenobiotic compounds. These cytosolic enzymes are different in their tissue distributions and substrate specificities. The gene structure (number and length of exons) is similar among family members. This gene encodes a phenol sulfotransferase with thermolabile enzyme activity. Four sulfotransferase genes are located on the p arm of chromosome 16, this gene and SULT1A3 arose from a segmental duplication. Read-through transcription exists between this gene and the upstream SLX1B (SLX1 structure-specific endonuclease subunit homolog B) gene that encodes a protein containing GIY-YIG domains. [provided by RefSeq, Nov 2010] |
UniProt Code: | P0DMM9 |
NCBI GenInfo Identifier: | 678019022 |
NCBI Gene ID: | 445329 |
NCBI Accession: | P0DMM9.1 |
UniProt Secondary Accession: | P0DMM9,O95603, P50224, Q1ET66, Q6ZWJ5, B4DNV0, |
UniProt Related Accession: | P0DMN0 |
Molecular Weight: | 34kDa |
NCBI Full Name: | Sulfotransferase 1A3 |
NCBI Synonym Full Names: | sulfotransferase family 1A member 4 |
NCBI Official Symbol: | SULT1A4 |
NCBI Official Synonym Symbols: | HAST3; M-PST; ST1A4; TL-PST; ST1A3/ST1A4 |
NCBI Protein Information: | sulfotransferase 1A4 |
UniProt Protein Name: | Sulfotransferase 1A3 |
UniProt Synonym Protein Names: | Aryl sulfotransferase 1A3/1A4; Catecholamine-sulfating phenol sulfotransferase; HAST3; M-PST; Monoamine-sulfating phenol sulfotransferase; Placental estrogen sulfotransferase; Sulfotransferase 1A3/1A4; Sulfotransferase, monoamine-preferring; Thermolabile phenol sulfotransferase; TL-PST |
Protein Family: | Sulfotransferase |
UniProt Gene Name: | SULT1A3 |