STOML2 Antibody (PACO45630)
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주문- SKU:
- PACO45630
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | STOML2 Antibody (PACO45630) |
Antibody SKU: | PACO45630 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, IHC |
Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200 |
Species Reactivity: | Human |
Immunogen: | Recombinant Human Stomatin-like protein 2, mitochondrial protein (29-356AA) |
Form: | Liquid |
Storage Buffer: | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Purification Method: | Antigen Affinity Purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
![]() | Immunohistochemistry of paraffin-embedded human lung cancer using PACO45630 at dilution of 1:100. |
![]() | Immunohistochemistry of paraffin-embedded human melanoma using PACO45630 at dilution of 1:100. |
Background: | Mitochondrial protein that probably regulates the biogenesis and the activity of mitochondria. Stimulates cardiolipin biosynthesis, binds cardiolipin-enriched membranes where it recruits and stabilizes some proteins including prohibitin and may therefore act in the organization of functional microdomains in mitochondrial membranes. Through regulation of the mitochondrial function may play a role into several biological processes including cell migration, cell proliferation, T-cell activation, calcium homeostasis and cellular response to stress. May play a role in calcium homeostasis through negative regulation of calcium efflux from mitochondria. Required for mitochondrial hyperfusion a pro-survival cellular response to stress which results in increased ATP production by mitochondria. May also regulate the organization of functional domains at the plasma membrane and play a role in T-cell activation through association with the T-cell receptor signaling complex and its regulation. |
Synonyms: | Stomatin-like protein 2, mitochondrial (SLP-2) (EPB72-like protein 2) (Paraprotein target 7) (Paratarg-7), STOML2, SLP2 |
UniProt Protein Function: | SLP-2: Belongs to the band 7/mec-2 family. |
UniProt Protein Details: | Protein type:Cytoskeletal; Mitochondrial Chromosomal Location of Human Ortholog: 9p13.1 Cellular Component: signalosome; extrinsic to plasma membrane; T cell receptor complex; cytoskeleton; mitochondrial inner membrane; mitochondrial intermembrane space; immunological synapse; lipid raft; actin cytoskeleton Molecular Function:protein binding; receptor binding Biological Process: cellular calcium ion homeostasis; mitochondrion organization and biogenesis; mitochondrial ATP synthesis coupled proton transport; interleukin-2 production; T cell receptor signaling pathway; mitochondrial calcium ion transport; protein oligomerization |
UniProt Code: | Q9UJZ1 |
NCBI GenInfo Identifier: | 60415944 |
NCBI Gene ID: | 30968 |
NCBI Accession: | Q9UJZ1.1 |
UniProt Secondary Accession: | Q9UJZ1,O60376, Q53G29, Q96FY2, Q9P042, B4E1K7, D3DRN3 |
UniProt Related Accession: | Q9UJZ1 |
Molecular Weight: | 356 |
NCBI Full Name: | Stomatin-like protein 2, mitochondrial |
NCBI Synonym Full Names: | stomatin (EPB72)-like 2 |
NCBI Official Symbol: | STOML2 |
NCBI Official Synonym Symbols: | SLP-2; HSPC108 |
NCBI Protein Information: | stomatin-like protein 2, mitochondrial; paratarg-7; stomatin-like 2; EPB72-like protein 2; paraprotein target 7 |
UniProt Protein Name: | Stomatin-like protein 2, mitochondrial |
UniProt Synonym Protein Names: | EPB72-like protein 2; Paraprotein target 7; Paratarg-7 |
Protein Family: | Stomatin-like protein |
UniProt Gene Name: | STOML2 |
UniProt Entry Name: | STML2_HUMAN |
Antibodies | ELISA Kits |
Anti-STOML2 Antibody (CAB10398) | Human STOML2 (Stomatin-like protein 2) ELISA Kit (HUFI06267) |
STOML2 Antibody (PACO12544) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
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