SSX5 Antibody (PACO20608)
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주문- SKU:
- PACO20608
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | SSX5 Antibody (PACO20608) |
Antibody SKU: | PACO20608 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB |
Recommended Dilutions: | ELISA:1:1000-1:2000, WB:1:200-1:1000 |
Species Reactivity: | Human |
Immunogen: | Synthetic peptide of human SSX5 |
Form: | Liquid |
Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Purification Method: | Antigen affinity purification |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
![]() | Gel: 12%SDS-PAGE, Lysate: 60 µg, Lane 1-3: A431 cells, Jurkat cells, Raji cells, Primary antibody: PACO20608(SSX5 Antibody) at dilution 1/200, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 30 seconds. |
Background: | The product of this gene belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins. These proteins may function as transcriptional repressors. They are also capable of eliciting spontaneous humoral and cellular immune responses in cancer patients, and are potentially useful targets in cancer vaccine-based immunotherapy. While some of the related SSX genes are involved in t(X;18)(p11.2;q11.2) translocations that are characteristically found in all synovial sarcomas, this gene does not appear to be involved in such translocations. |
Synonyms: | synovial sarcoma, X breakpoint 5 |
UniProt Protein Function: | Ssxb8: Could act as a modulator of transcription. Belongs to the SSX family. 2 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Cancer Testis Antigen (CTA) Chromosomal Location of Human Ortholog: Xp11.23 Cellular Component: nucleus Molecular Function:protein binding; transcription corepressor activity |
NCBI Summary: | The product of this gene belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins. These proteins may function as transcriptional repressors. They are also capable of eliciting spontaneous humoral and cellular immune responses in cancer patients, and are potentially useful targets in cancer vaccine-based immunotherapy. While some of the related SSX genes are involved in t(X;18)(p11.2;q11.2) translocations that are characteristically found in all synovial sarcomas, this gene does not appear to be involved in such translocations. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2013] |
UniProt Code: | O60225 |
NCBI GenInfo Identifier: | 115502458 |
NCBI Gene ID: | 6758 |
NCBI Accession: | O60225.3 |
UniProt Secondary Accession: | O60225,Q5JQ59, Q5JQ60, Q96AW3, |
UniProt Related Accession: | O60225 |
Molecular Weight: | 26,284 Da |
NCBI Full Name: | Protein SSX5 |
NCBI Synonym Full Names: | SSX family member 5 |
NCBI Official Symbol: | SSX5 |
NCBI Protein Information: | protein SSX5 |
UniProt Protein Name: | Protein SSX5 |
Protein Family: | Protein |
UniProt Gene Name: | SSX5 |
UniProt Entry Name: | SSX5_HUMAN |