SNX5 Antibody (PACO20570)
제품 코드를 사용하여 Assay Genie 메인 사이트를 통해 주문합니다.
주문- SKU:
- PACO20570
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | SNX5 Antibody (PACO20570) |
Antibody SKU: | PACO20570 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC |
Recommended Dilutions: | ELISA:1:2000-1:5000, WB:1:500-1:2000, IHC:1:25-1:100 |
Species Reactivity: | Human, Mouse, Rat |
Immunogen: | Synthetic peptide of human SNX5 |
Form: | Liquid |
Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Purification Method: | Antigen affinity purification |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
![]() | Gel: 8%SDS-PAGE, Lysate: 40 µg, Lane 1-2: K562 cells, Jurkat cells, Primary antibody: PACO20570(SNX5 Antibody) at dilution 1/250, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute. |
![]() | The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using PACO20570(SNX5 Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: x200). |
Background: | This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein functions in endosomal sorting, the phosphoinositide-signaling pathway, and macropinocytosis. This gene may play a role in the tumorigenesis of papillary thyroid carcinoma. Alternative splicing results in multiple transcript variants encoding different isoforms. |
Synonyms: | sorting nexin 5 |
UniProt Protein Function: | SNX5: May be involved in several stages of intracellular trafficking. Plays a role in macropinocytosis. Plays a role in the internalization of EGFR after EGF stimulation. Belongs to the sorting nexin family. |
UniProt Protein Details: | Protein type:Vesicle Chromosomal Location of Human Ortholog: 20p11 Cellular Component: ruffle; extrinsic to internal side of plasma membrane; cytoplasmic vesicle membrane; early endosome membrane; retromer complex; phagocytic cup Molecular Function:protein binding; phosphoinositide binding Biological Process: pinocytosis; intracellular protein transport; vesicle organization and biogenesis; retrograde transport, endosome to Golgi |
NCBI Summary: | This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein functions in endosomal sorting, the phosphoinositide-signaling pathway, and macropinocytosis. This gene may play a role in the tumorigenesis of papillary thyroid carcinoma. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Sep 2013] |
UniProt Code: | Q9Y5X3 |
NCBI GenInfo Identifier: | 10720289 |
NCBI Gene ID: | 27131 |
NCBI Accession: | Q9Y5X3.1 |
UniProt Secondary Accession: | Q9Y5X3,Q52LC4, Q7KZN0, Q9BWP0, B7ZKN3, D3DW26, |
UniProt Related Accession: | Q9Y5X3 |
Molecular Weight: | 404 |
NCBI Full Name: | Sorting nexin-5 |
NCBI Synonym Full Names: | sorting nexin 5 |
NCBI Official Symbol: | SNX5 |
NCBI Protein Information: | sorting nexin-5 |
UniProt Protein Name: | Sorting nexin-5 |
Protein Family: | Sorting nexin |
UniProt Gene Name: | SNX5 |
UniProt Entry Name: | SNX5_HUMAN |